The present invention provides cDNAs encoding human and murine RENT1 (regulator of nonsense transcripts). rent1 is the first identified mammalian protein that contains all of the putative functional elements in Upf1p including zinc finger-like motifs and NTPase domains as well as all motifs common ...
2.to adjust (a piece of machineryetc) so that it works at a certain rateetc.Can you regulate this watch so that it keeps time accurately?regular ˌreguˈlationnoun 1.a rule or instruction.There are certain regulations laid down as to how this job should be done, and these must be...
Sign up with one click: Facebook Twitter Google Share on Facebook regulator problem [′reg·yə‚lād·ər ‚präb·ləm] (control systems) linear regulator problem McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc. ...
The factor, variously referred to as Rent1 (regulator of nonsense transcripts) or HUPF1 (human Upf1 protein), was identified by isolating cDNA for a ... X Sun,HA Perlick,DLE Maquat - 《Proc Natl Acad Sci U S A》 被引量: 455发表: 1998年 A mutated human homologue to yeast Upf1 ...
Regulator of Nonsense Transcripts 1 regulator of ribosome biogenesis 1 homolog Regulator of Stationary Phase A regulator pin Regulator Pressure, Water regulator problem Regulator Sluice Regulator, Growth Regulator, Growth Regulator, Growth Regulator, Growth Regulator/Rectifier regulatored regulatored regulatored...
RNA-binding protein IGF2BP3 targeting of oncogenic transcripts promotes hematopoietic progenitor proliferation. J Clin Invest. 2016;126:1495–511. Article Google Scholar Radine C, Peters D, Reese A, Neuwahl J, Budach W, Janicke RU, et al. The RNA-binding protein RBM47 is a novel ...
In parallel, mTECs express a number of TSA transcripts (such as GAD67, C-reactive protein), which are not regulated by Aire (Derbinski et al., 2005). However, Aire also controls the expression of non-TSA genes, which are physically clustered on chromosomes (Johnnidis et al., 2005; ...
The two frameshift variants result in a premature termination codon in the last exon, and the mutant transcripts are predicted to escape nonsense mediated decay and cause loss of a C-terminal nuclear localization signal required for NSRP1 function. Conclusion We establish NSRP1 as a gene for a ...
Moreover, Morf-deficient mice still carry residual transcripts (43), and the total knock-out may yield more dramatic phenotypes. As Brpf1 interacts with both Moz and Morf, as suggested by cell-based studies (10, 14, 16), its loss may affect the function of both to yield the severe ...
To examine whether PHO2/miRNA399 links to increased accumulation of Pi in bik1 plants, we analyzed the changes in levels of PHO2 expression and two miRNA399 primary transcripts, miRNA399a and miRNA399d, in bik1 seedlings grown under + Pi and –Pi conditions. The expression level of PHO2...