Two independent mutants of Escherichia coli K12 have been isolated which have lost the capacity to be induced by β-galactosides for the production of the proteins governed by the lactose Operon in E. coli. These mutations are located in the regulator ( i) gene of the Lac region. In ...
According to the lac-operon concept, which functional unit of the bacterial gene material is responsible for suppressing the activity of the operator gene in the absent of lactose? Promoter gene Repressor protein Regulator gene Structural gene A Promoter gene B Regulator gene ...
motifs residing in the single-stranded loop regions. Most frequently, one GGA motif is part of the ribosome binding site of the target gene, and CsrA-binding prevents the attachment of ribosomes, resulting in the downregulation of protein translation and a faster mRNA degradation15. On the othe...
like proteins can be carried on mobile genetic elements. This raises the possibility that horizontal gene transfer expands the repertoire of protein–protein interactions that nucleoid-associated proteins can engage in, with potentially profound consequences for the global gene-expression profile of the ...
A regulator protein is a type of protein that binds to a specific DNA sequence in response to the presence of a small-molecule inducer. These proteins play a key role in controlling gene expression in various biological processes. AI generated definition based on: Methods in Enzymology, 2011 ...
wblE is evidently an essential gene in Streptomyces; an attempt to delete it in S. coelicolor was also unsuccessful13. When wblE was overexpressed in ATCC31267, the resulting strain had a phenotype similar to that of Drex (Fig. 5), suggesting that Rex regulates morphological differentiation ...
In the absence of the choline-responsive repressor GbsR, opuB expression is also suppressed by choline. We also report that a gene (formerly yvbF, now designated opcR) located immediately upstream of the opuC operon negatively regulates transcription of the opuC operon and, in the absence of...
eutropha JMP134 not only controls the expression of the o-phe- nylene diene gene cluster tfdDCEFB, but also regulates the transcription of tfdA to metabolize 2,4-dichlorophe- noxyacetic acid isooctyl ester [5]. Moreover, LttRs regu- late the genes involved in virulence, metabolism, quorum...
In low-copper conditions, a CopR dimer in the zinc form is bound to the cop box in front of the copRZA operon and the copB gene. When CopZ donates Cu+ to CopR, one Zn2+ per CopR monomer is replaced by two Cu+, with concomitant release of CopR from the promoters and induction ...
3d). To test whether the localization of CcrZ depends on FtsZ, we constructed a strain expressing CcrZ–mKate2 as well as a second copy of FtsZ under the control of an IPTG-inducible promoter and deleted the native ftsZ gene (ftsZ−/+). As expected, FtsZ depletion led to aberrant ...