Human body thermal regulationTwo-node modelSystem dynamicsOutdoor thermal comfortThermal comfort of people in outdoor urban spaces is a growing concern in cities due to climate change and urbanization. In outdoor settings the climate and behavior of people are more dynamic than in indoor situations...
Human leukocyte antigen class I A class of proteins on the cell surface that have a critical role in immune system recognition and response by presenting antigenic peptides to cytotoxic T cells. Invariant natural killer T cells A distinct population of T cells that express an invariant T cell ...
Immunology was founded by studying the body's response to infectious microorganisms, and yet microbial prokaryotes only tell half the story of the immune system. Eukaryotic pathogens — protozoa, helminths, fungi and ectoparasites — have all been powerf
Selective expression of regulators of G-protein signaling (RGS) in the human central nervous system. The human tissue distribution of the nineteen known human regulators of G-protein signaling (RGS) is described. Measurement of RGS mRNA levels in human bra... C Larminie,P Murdock,JP Walhin,...
freight railroads are once again the top-performing freight rail system in the world,” Marc Scribner…told the Washington Examiner. …”Over the past 40 years, rail traffic has doubled … rail rates are down more than 40% when adjusted for inflation … and recent years have been the ...
Autonomic regulation of all the different body functions requires the existence of anatomically and functionally specific neuronal pathways in the periphery and a specific organization in the central nervous system. Otherwise it would not be possible to have the precision and flexibility of control and ...
Studies investigating genetic variation in human ACKRs and the effect of ACKR deficiency in mice and zebrafish have showed that some ACKRs have key developmental and homeostatic functions in the immune system and elsewhere. ACKRs have emerged as important regulators of immune and inflammatory response...
IL-2 was first identified as a growth factor capable of driving the expansion of activated human T cell populations. In the more than 40 years since its discovery, a tremendous amount has been learned regarding the mechanisms that regulate the expression of both IL-2 and its cell surface rece...
The dynamic expression of individual tRNA genes during cellular differentiation supports a more complicated structure governing nascent tRNA levels than simply tDNA copy number. Instead, differential transcription of human tRNA genes may provide a system for refining cellular tRNA pools towards cell-type-...
A. Ciechanover, Intracellular protein degradation: From a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting, Biochim. Biophys. Acta 1824 (2012) 2–12. Google Scholar [7] B. Turk, V. Turk Lysosomes as “suicide bags” in cell death:...