Cellular biology Regulation of tissue remodeling through the calreticulin binding domain of thrombospondin-1 THE UNIVERSITY OF ALABAMA AT BIRMINGHAM Joanne E. Murphy-Ullrich SweetwyneMariya TThrombospondin-1 (TSP1) is a multifunctional matricellular protein released by platelets in response to injury and ...
Bone remodeling is a lifelong process that gives rise to a mature, dynamic bone structure via a balance between bone formation by osteoblasts and resorption by osteoclasts. These opposite processes allow the accommodation of bones to dynamic mechanical forces, altering bone mass in response to changin...
Although mechanical regulation of cell function and tissue remodeling has long been appreciated in other contexts, the purpose of this review is to highlight the increasing appreciation of its importance in fibrosis and hypertrophic scarring.Recent findings;Experiments in both animal and cellular model ...
Dynamic transcriptional activity and chromatin remodeling of regulatory T cells after varied duration of interleukin-2 receptor signaling Article 21 April 2022 TIM-3 drives temporal differences in restimulation-induced cell death sensitivity in effector CD8+ T cells in conjunction with CEACAM1 Article...
In each reproductive cycle, extensive tissue remodeling takes place in the ovary during follicular development, ovulation, formation and regression of corpus luteum (CL) and follicular atresia. Several lines of indirect evidence suggest that these changes are mediated, in part, by proteases belonging ...
Angiogenesis, the process of new capillary formation from a pre-existing vessel plays an essential role in both embryonic and postnatal development, in the remodeling of various organ systems, and in several pathologies, particularly cancer. In the last 20 years of angiogenesis research, a variety ...
the expression of this protein and underlines that its level and activity are influenced by multiple stimuli. Another level of regulation is represented by alternative splicing. Tissue-specific expression ofMITF,TFEB, andTFECseems to be mediated, at least in part, by alternative transcription start ...
Developmental and hormonal regulation of midgut remodeling in a lepidopteran insect, Heliothis virescens. Midgut tissue undergoes remodeling during metamorphosis in insects belonging to orders Lepidoptera and Diptera. We investigated the developmental and hormo... R Parthasarathy,SR Palli - 《Mechanisms of ...
Tissue maintenance and repair depend on the integrated activity of multiple cell types1. Whereas the contributions of epithelial2,3, immune4,5 and stromal cells6,7 in intestinal tissue integrity are well understood, the role of intrinsic neuroglia networks remains largely unknown. Here we uncover ...
Bone is a dynamic hard tissue with a tertiarily-mineralized extracellular matrix and robust self-renewal capacities, undergoing a process of continuous bone cell replacement via various mesenchymal progenitors, known as bone remodeling. This ongoing cellular synchronization of bone remodeling and ...