Stanton P G.Regulation of the blood-testis barrier[J].Semin Cell Dev Biol,2016,59:166-173.Stanton PG 2016 Regulation of the blood-testis barrier. Seminars in Cell and Developmental Biology 59 166-173. (doi:10.1016/j. semcdb.2016.06.018)...
An in vivo model was used to investigate the regulation of tight junction (TJ) dynamics in the testis when adult rats were treated with CdCl2. It was shown that the CdCl2-induced disruption of the blood-testis barrier (BTB) associated with a transient induction in testicular TGF-β2 and ...
The blood-testis barrier (BTB) provides an efficient barrier to restrict paracellular and transcellular transport of substances, such as toxicants and drug... L Su,DD Mruk,CY Cheng - 《Spermatogenesis》 被引量: 9发表: 2012年 The regulation of testis function From this review it is evident th...
Specialized adhesion junctions are formed between adjacent Sertoli cells that in total form the blood testis barrier (BTB) near the basement membrane of the seminiferous tubules. The BTB divides the seminiferous tubule into basal and adluminal compartments. During the initial preleptotene stage of ...
Lui WY, Wong CH, Mruk DD, Cheng CY 2003 TGF-3 regulates the blood- testis barrier dynamics via the p38 mitogen activated protein (MAP) kinase pathway: an in vivo study. Endocrinology 144:1139 –1142 43. Lee NPY, Mruk DD, Conway AM, Cheng CY 2004 Zyxin, axin, and Wiskott- ...
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous system (CNS) from toxins and pathogens in blood. However, the presence of BBB complicates the pharmacotherapy for CNS disorders as the most chemical drugs and bioph
The distribution of drug-efflux pumps, P-gp, BCRP, MRP1 and MRP2, in the normal blood-testis barrier and in primary testicular tumours. The drug-efflux pumps -glycoprotein (-gp) and multidrug resistance-associated protein 1 (MRP1) are present in the blood鈥搕estis barrier (BTB) and may ...
Regulation of Blood–Brain Barrier Permeability. Mayhan, W. G., Regulation of blood-brain barrier permeability. (2001) Microcirculation 8, 89-104.Mayhan WG. Regulation of blood-brain barrier ... MAYHAN,WILLIAM,G - 《Microcirculation》 被引量: 182发表: 2001年 ...
Spermatogonia are situated below the blood–testis barrier and comprise the germ stem cell compartment. Monitoring the genetic quality of these male germ stem cells is of critical importance to preserve germ-line integrity and ensure the evolutionary survival of a species. The very high replication ...
The decrease of AhR mRNA level after treatment with TCDD was revealed also by other authors [21]. The physiological components of the blood-testis and –epididymis barrier consist of drugs, lipids, metabolites and ions transporters. Show abstract Paternal smoking and germ cell death: A mechanistic...