Stagsted. Regulation of receptor internalization by the major histocompatibility complex class I molecule. Proc. Natl. Acad. Sci. USA 91: 9086–9090 (1994).Stagsted J.Regulation of receptor internalization by major histo- compatibility complex class I (MHOI) and effect of peptides derived from...
CBD Versus CBDP: Comparing In Vitro Receptor-Binding Activities Phytocannabinoids with seven-carbon alkyl chains (phorols) have gained a lot of attention, as they are commonly believed to be more potent versions of typi... M Haghdoost,S Young,AK Holloway,... - 《International Journal of Mo...
TGF-beta latency protein 1 (), which facilitates the release and activation of L-, is also important in the biology of .: Open lung biopsy samples ... Khalil,N - 《Thorax》 被引量: 288发表: 2001年 Caveolin-1, TGF-β receptor internalization, and the pathogenesis of systemic sclerosis ...
thusimplicatingaroleforthe ubiquitinationmachineryinthetraffickingofthe 2 AR.Receptorubiquitination required -arrestin,whichboundtotheE3ubiquitinligaseMdm2.Abrogation of -arrestinubiquitination,eitherbyexpressioninMdm2-nullcellsorby dominant-negativeformsofMdm2lackingE3ligaseactivity,inhibitedreceptor internalization...
of the receptor toG proteinsand by ligand-inducedinternalizationof the receptor. As opposed to the fairly rapid process of controlling PAF availability and PAF receptor responsiveness, long-term regulation of the PAF receptor includes alterations in PAFreceptor expression. Transient elevation of cyclic AM...
of the receptor.152Receptor regulatory responses to CT are likely to be cell or tissue dependent. For example, in mouse or rat osteoclasts, a potent downregulation of CTR mRNA appears to be mediated by a cAMP-dependent mechanism, in addition to downregulation of the receptor by internalization....
In vascular smooth muscle cells, the hormone angiotensin II is thought to cause internalization of the seven-transmembrane domain type 1 angiotensin II receptor (AT1-R) but it also suppresses expression of the receptor mRNA. As for similarly regulated members of this gene superfamily, the relative...
Epidermal Growth Factor Receptor Down-regulation Induced by UVA in Human Keratinocytes Does Not Require the Receptor Kinase Activity Activation of the epidermal growth factor (EGF) receptor by EGF, its ligand, results in receptor internalization and down-regulation, which requires recept... YY He,JL...
Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization. Cell 141, 859–871 (2010). Article PubMed PubMed Central CAS Google Scholar Goebbels, S. et al. Genetic targeting of principal neurons in neocortex and hippocampus of NEX-Cre mice. ...
5e, f). Furthermore, we observed that under confinement, receptor internalization and therefore EGFR activation was restricted to the periphery of the MCF10A cell cluster (Fig. 6d, left panel, Supplementary Fig. 14 for MCF12A and HMECt cells), a situation clearly reminiscent of the previously...