(2013) Regulation of glycogen synthase from mammalian skeletal muscle--a unifying view of allosteric and covalent regulation. FEBS J. 280, 2-27 doi:10.1111/febs.12059Palm DC, Rohwer JM, Hofmeyr JH. Regulation of glycogen synthase from mammalian skeletal muscle--a unifying view of allosteric ...
The major yeast glycogen synthase, Gsy2p, is inactivated by phosphorylation and activated by the allosteric ligand glucose-6-P. From studies of recombinant proteins, the control can be accommodated by a three-state model, in which unphosphorylated enzyme has intermediate activity (state II). Glucos...
Regulation of glycogen synthase kinase-3 (GSK-3) and β-catenin by CD40 in B lymphocytes 来自 circle.ubc.ca 喜欢 0 阅读量: 63 作者: BJ Biagioni 摘要: Antibodies are specialized molecules produced by B-lymphocytes to combat infection by binding to and targeting infectious agents for destruction...
Cedazo-Minguez A, Popescu BO, Blanco-Millan JM, et al. Apolipoprotein E and beta-amyloid (1- 42) regulation of glycogen synthase kinase-3beta. J Neurochem 2003;87(5):1152-1164. [PubMed: 14622095]Cedazo-Minguez A, Popescu BO, Blanco-Millan JM, Akterin S, Pei JJ, Win- blad B, ...
Since the activation of each signaling pathway results in a decrease in GSK3β activity, we examined the specificity of their downstream effects in the same cell type. Insulin induces an increased activity of glycogen synthase but has no influence on the protein level of β-catenin. In contrast...
Glycogen synthase activity is a key component in the regulation of glycogen resynthesis. Glycogen synthase enzyme exists in 2 states: the less active, more phosphorylated (D) form which is under allosteric control of glucose-6-phosphate, and the more active, less phosphorylated (I) form which is...
Phosphorylation of Axin, a Wnt Signal Negative Regulator, by Glycogen Synthase Kinase-3\\u00a0 Regulates Its Stability Yamamoto,H.,Kishida,... - 《Journal of Biological Chemistry》 被引量: 783发表: 1999年 Mechanisms of Signal Transduction: Novel inflammatory role for glycogen synthase-3 β in...
Accumulating evidence suggests that glycogen synthase kinase 3 (GSK-3) is a multifunctional kinase implicated in neuronal development, mood stabilization, and neurodegeneration. However, the synaptic actions of GSK-3 are largely unknown. In this study, we examined the impact of GSK-3 on AMPA recept...
R. The regulation of glycogen synthase by protein phosphatase 1 in 3T3-L1 adipocytes. Evidence for a potential role for DARPP-32 in insulin action. J. Biol. Chem. 272, 29698–29703 (1997). CAS PubMed Google Scholar Newgard, C. B., Brady, M. J., O'Doherty, R. M. & Saltiel, ...
F. (2003). Apolipoprotein E and β-amyloid (1-42) regulation of glycogen synthase kinase-3β. J Neurochem 87, 1152-1164.Cedazo-Minguez A, Popescu BO, Blanco-Millan JM, Akterin S, Pei JJ, Winblad B and Cowburn RF. Apolipoprotein E and β-amyloid (1-42) regul...