Tellez-Inon, MT, Torres, HN (1973) Regulation of glycogen phosphorylase a phosphatase in Neurospora crassa. Biochim Biophys Acta 297: pp. 399-412Téllez De I nón MT, Torres HN. Regulation of glycogen phosphorylase a phosphatase in Neurospora crassa. Biochim Biophys Acta. 1973 Feb 28; 297 (...
The adrenal glands release the hormone epinephrine, sometimes known as adrenaline, during times of stress or physical activity. To provide a quick supply of glucose for energy, epinephrine triggers the breakdown of glycogen. Glycogen phosphorylase is phosphorylated and activated by PKA, which also inh...
On the other hand, glycogen degradation requires the glycogen debranching enzyme (GDE; GlgX), which directly catalyzes the hydrolysis of α-(1→6)-linked glucose residues and the glycogen phosphorylase (GP; GlgP) to generate glucose-1-phosphate, which feeds into primary metabolism7. An ...
Glucose accesses the brain primarily via the astrocyte cell compartment, where it passes through the glycogen shunt before catabolism to the oxidizable fuel L-lactate. Glycogen phosphorylase (GP) isoenzymes GPbb and GPmm impose distinctive control of ventromedial hypothalamic nucleus (VMN) glucose-reg...
Acetylation negatively regulates glycogen phosphorylase by recruiting protein phosphatase 1. Cell Metab. 2012;15:75–87. Article CAS PubMed PubMed Central Google Scholar Wang YP, Zhou LS, Zhao YZ, Wang SW, Chen LL, Liu LX, et al. Regulation of G 6 PD acetylation by SIRT2 and KAT9 ...
Starch phosphorylase (SP) is an enzyme used for the reversible phosphorolysis of the 伪-glucan in plant cells. When compared to its isoform in an animal cell, glycogen phosphorylase, a peptide containing 78 amino acids (L78) is inserted in the centre of the low-affinity type starch ...
45. Therefore, PF is negatively correlated with the local Gibbs free energy (ΔG)45. Our previous work, as well as Phillips’s work, successfully used the PF extracted from HDX-MS data to assess local stability changes within the allosteric regulation of glycogen phosphorylases46,47. Apart ...
Asencion Diez MD, Demonte AM, Guerrero SA, Ballicora MA, Iglesias AA (2013) The ADP-glucose Pyr- ophosphorylase from Streptococcus mutans Provides Evidence for the Regulation of Polysaccharide Biosynthesis in Firmicutes. Mol Microbiol.Asencion Diez MD, Demonte AM, Guerrero SA, Ballicora MA, ...
The role of glycogenolytically-derived ATP was studied by the use of glycogen phosphorylase inhibitors and glycogen lowering treatment in mechanically skinned fibers, which invariably prolonged repriming time, strongly indicating an attenuated NKA activity (Jensen et al. 2020), further supporting the ...
There are also enzymes regulated by the covalent addition or subtraction of groups. An example of this is glycogen phosphorylase, the enzyme that initiates the glycogen degradation pathway. This enzyme is in a state of low activity, called phosphorylase b, which is converted to active phosphorylase...