T cell signal regu- lation by the actin cytoskeleton. J. Biol. Chem. 285: 14737-14746.G.R. Chichili, A.D. Westmuckett, W. Rodgers, T cell signal regulation by the actin cytoskeleton, J. Biol. Chem. 285 (2010) 14737-14746....
The dynamic remolding of the actin cytoskeleton is a critical part of most cellular activities, and malfunction of cytoskeletal proteins results in various human diseases. The transition between two forms of actin, monomeric or G-actin and filamentous or F-actin, is tightly regulated in time and...
必应词典为您提供regulation-of-actin-cytoskeleton的释义,网络释义: 肌动蛋白细胞骨架调节;调节肌动蛋白细胞骨架;
Actin is one of the most abundant proteins expressed in a cell and is also one of the most highly conserved proteins. These facts point to the fundamental importance of actin in biology. The actin cytoskeleton may be seen as a mechanism that allows extracellular signals to be relayed from the...
In addition, myocardin-stimulated Smad2 phosphorylation and RhoA expression, leading to increased expression of type 1 collagen in an actin cytoskeleton-dependent manner. Myocardin also directly enhanced SRF expression and stimulated collagen 1α1 and 1α2 promoter activities. In addition, overexpression ...
Unlike 3T3-L1 cells, these DFAT cells do not undergo spontaneous adipogenesis, with the adipocytic differentiation of DFAT cells thus being more tightly controlled than that of 3T3-L1 cells12,13. Here, we examine the roles of actin cytoskeleton remodelling in adipocytic differentiation by using...
MicroRNA expression signature of oral squamous cell carcinoma: functional role of microRNA-26a/b in the modulation of novel cancer pathways. Silencing of TMEM184B inhibited cancer cell migration and invasion, and regulated the actin cytoskeleton-pathway related genes.Loss of tumour-suppressive miR-....
该实验旨在探讨 Wnt/β-catenin 信号通路在主动脉瓣钙化机制中的调控作用。方法:进行主动脉瓣瓣膜间质细胞的分离和培养,用刺激因素 ox-LDL 进行干预,使 瓣膜间质细胞向成骨细胞样表型转化,采用 Western Blotting 技术和 Real Time-PCR 技术检测已成功向成骨细胞样表型转化的瓣膜间质细胞 Wnt/β-catenin 信号通路...
Although many responses initiated by DNA damage have been character- ized, the role of actin cytoskeleton regulators is largely unknown. We now show that RhoC and LIM kinase 2 (LIMK2) are direct p53 target genes induced by genotoxic agents. Although RhoC and LIMK2 have well-established roles ...
The plant cytoskeleton, consisting of actin filaments and microtubules, is a highly dynamic filamentous framework involved in plant growth, development, and stress responses. Recently, research has demonstrated that the plant cytoskeleton undergoes rapid remodeling upon sensing pathogen attacks, coordinating ...