Self-regulation of NF-κB activity and COX-2 expression. In inflammatory reactions, NF-κB is activated and, partly as a result of this, an increase in expression and activity of enzymes of the prostaglandin synthesis pathway takes place. Released AA is converted into PGD2or PGE2. In inflamma...
155,156,157 Low-intensity vibration (LIV) or mechanical strain can cause a rapid and transient β-catenin association with the nucleoskeleton through the FAK-mediated inhibition of GSK-3β (Fig. 4a). β-catenin molecules that do not bridge cadherins to the actin cytoskeleton or translocate ...
Research history of dietary regulation. The advances in dietary regulation can be roughly divided into three stages. Stage I, dietary regulation discovery and initial characterizations of their effects on body function, including dietary interventions based on traditional eating habits, such as fasting,36...
Ser9, causing increased β-catenin level [154]. Consistent with this result, overexpression of GSK3β-Ser9A (serine mutated to alanine) abolishes insulin and IGF-1 (Insulin-like growth factor-1)-induced activation of β-catenin-dependent transcription [155]. However, the observations that GSK3...
Neurotrophin stimulation of tropomyosin-related kinase (Trk) and p75 receptors influences cellular processes such as proliferation, growth, differentiation... A Blöchl,R Blöchl - 《Journal of Neurochemistry》 被引量: 156发表: 2010年 p75NTR‐mediated signaling promotes the survival of myoblasts an...
来自 Semantic Scholar 喜欢 0 阅读量: 155 作者:Charles A. West,R. Ray Fall 摘要: Studies of the mode of action of a family of plant hormones are of great interest to the plant physiologist. But at the same time the mechanisms which govern the production of that group of growth ...
As social stress is the most severe [154] and unpredictable [155] of stressors, it specifically promotes maladaptive behavior, including depression, anxiety, PTSD, sociophobia, loss of self-esteem, and other behavioral symptoms in humans [151,153]. The incidence rates of adult affective ...
and LC, structural dynamics analysis was performed. The binding model was obtained by molecular docking (Supplementary Fig.6). The carbonyl group and the cyano group of LC form three pairs of hydrogen bonds interacting with the hydroxyl groups of GLN92, ASN155, and GLN156 of GST_119, ...
155-174Magnuson MA, Niswender KD, Pettepher ... ML Markwardt,KM Seckinger,MA Rizzo - American Society for Biochemistry and Molecular Biology 被引量: 0发表: 2016年 [Frontiers in Diabetes] Glucokinase and Glycemic Disease: From Basics to Novel Therapeutics Volume 16 || Molecular Biology of ...
plays significant roles in PD pathogenesis155,156. Because of the inflammatory nature of PD and the potential roles of microbiota and gut metabolites in regulating PD, we also include a discussion of PD in this review (Tables1,2). Both genetics and environmental factors, such as diet and expo...