Children younger than age 6: 0.1 mg/kg I.V. as a single dose ➣ Diabetic gastroparesis Adults: 10 mg P.O. 30 minutes before meals and at bedtime for 2 to 8 weeks. If patient can't tolerate P.O. doses, give same dosage I.V. or I.M. ➣ Gastroesophageal reflux Adults: 10 ...
Dosage For Acute And Recurrent Diabetic Gastroparesis The recommended adult dosage for the treatment of acute and recurrent diabetic gastroparesis is 10 mg four times daily for 2 to 8 weeks, depending on symptomatic response. Avoid Reglan treatment for greater than 12 weeks [seeWARNINGS AND PRECAUTIO...
Hemodialysisremoves relatively little metoclopramide, probably because of the small amount of the drug in blood relative to tissues. Similarly, continuous ambulatoryperitoneal dialysisdoes not remove significant amounts of drug. It is unlikely that dosage would need to be adjusted to compensate for losse...
Children, elderly. Renal or hepatic impairment, porphyria, epilepsy, Parkinson’s disease, history of depression. Ability to drive or operate machineries may be impaired. Pregnancy and lactation. Monitor patients on prolonged therapy. Increased risk of tardive dyskinesia in patients on prolonged or hig...
Safety and effectiveness in pediatric patients have not been established (see OVERDOSAGE). Care should be exercised in administering metoclopramide to neonates since prolonged clearance may produce excessive serum concentrations (see CLINICAL PHARMACOLOGY – Pharmacokinetics). In addition, neonates have reduce...