2010. Effects of cis- regulatory variation differ across regions of the adult human brain. Hum Mol Genet 19:4490-4496.Buonocore F, Hill MJ, Campbell CD, Oladimeji PB, Jeffries AR, Troakes C et al. Effects of cis-regulatory variation differ across regions of the adult human brain. Hum ...
The regulation of systemic iron is through the proteins transferrin (iron mobilization) and ferritin (iron sequestration). This study examines the cellular and regional distribution of iron and the iron-related proteins ferritin and transferrin in selected regions of the adult and aged rat brain. ...
As a paradigm for tissue aging and functional decline in the brain, we focused on the neurogenic region located in the subventricular zone (SVZ) of the adult mammalian brain. The SVZ neurogenic region (or ‘niche’) contains neural stem cells (NSCs) that give rise to differentiated cells (ne...
Active cell proliferation also occurs in the subventricular zone (SVZ) of the lateral ventricle and, to a lesser extent, throughout white and gray matter regions of the adult brain. The aim of the present study was to determine whether extrahippocampal cell proliferation is also affected by ...
We assayed calpain activity in 27 human brain regions from adult (43–65 years of age) and aged (66–83 years of age) postmortem tissue samples. Calpain I (M Ca-requiring) activity was 10% or less of the total activity; it was below detectable levels in a number of areas, and so ...
The present study deals with the effect of atrazine on nitrogen metabolism in the liver and brain of fish. Significant changes were seen in the levels of proteins, free amino acids, ammonia, urea, glutamine and the activity levels of proteases, glucogenic aminotransferases, branched-chain ...
Expression of Menkes AtPase and Wilson ATPpase in different regions of the adult rat brain. N,A,Platonova,... - 《Doklady Biological Sciences Proceedings of the Academy of Sciences of the Ussr Biological Sciences》 被引量: 2发表: 2005年 Correction of the Copper Transport Defect of Menkes ...
THE PERMEABILITY TO P32 IN DIFFERENT REGIONS OF THE BRAIN OF NEW-BORN AND ADULT RABBITS; AN INVESTIGATION OF THE BLOOD-BRAIN BARRIER.ANIMALS, NEWBORNBLOOD-BRAIN BARRIERBRAINBRAIN CHEMISTRYBRAIN PHYSIOLOGYBRAIN STEMCEREBELLUMCEREBRAL CORTEXEXPERIMENTAL LAB STUDYGANGLIA, BASAL...
The erbAα2 protein has been shown to inhibit the T3 inductive effects of functional receptors, and α2 mRNA is expressed at high levels in adult rat brain. Thus, expression of erbAα2 may explain the observation that adult rat brain is not a T3 responsive organ, despite the presence of ...
We have previously identified a network of higher-order brain regions particularly vulnerable to the ageing process, schizophrenia and Alzheimer’s disease. However, it remains unknown what the genetic influences on this fragile brain network are, and wh