Meaning This study demonstrates the potential utility of evinacumab as an effective and generally well-tolerated LLT for patients with refractory hypercholesterolemia. Abstract Importance Patients with refractory hypercholesterolemia who do not achieve their guideline-defined low-density lipoprotein cholesterol ...
For each item or domain, the taxonomy specified a collection of common terms and statements used to convey the same or related ideas. By assigning the most closely related keywords, reviewers used the taxonomy to organise the statements they extracted according to its meaning and content [23]. ...
Accordingly, depression is usually considered resistant or refractory when at least 2 trials with antidepressants from different pharmacologic classes (adequate in terms of dosage, duration, and compliance) fail to produce a significant clinical improvement. Regarding diagnostic assessments, an accurate and...
T-cells, a type of lymphocyte that plays a role in the immune system, become cancerous and develop into skin lesions, leading to a decrease in the quality of life of patients with this disease due to
“These data provide further validation of our proprietary TriTAC T cell engager platform, demonstrating robust clinical activity for HPN217 at higher doses, while maintaining tolerability in this heavily refractory patient population,” said ...
Meaning In patients with imminent BSI, it appears that mcfDNA-seq can identify clinically relevant pathogens days before onset of attributable symptoms. Abstract Importance Bloodstream infection (BSI) is a common, life-threatening complication of treatment for cancer. Predicting BSI before onset of clin...
This press release contains forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are statements that are not historical facts, and in some cases can be identified by terms such as "may,"...
FDAApprovalsBest Places to Work MORE ON THIS TOPIC FDA Novavax Shares Slide as FDA Pauses COVID/Flu Vaccine Candidates October 16, 2024 · 1 min read · Annalee Armstrong Drug shortages Lilly’s Tirzepatide Could Land Again on FDA Drug Shortage List...
meaning that the suitability of these indications for treatment with CLDN6-directed CAR-T cells remains unclear. Treatment of more patients with standardized CARVac treatment algorithms are required to draw clear conclusions about the potential role of CARVac in supporting CAR-T cell engraftment and pe...
The expression “and/or” in connection with three or more recited objects should be understood to have the same meaning unless otherwise understood from the context.The use of the term “include,”“includes,”“including,”“have,”“has,”“having,”“contain,”“contains,” or “containing...