Hormonal Etiology of Epithelial Ovarian Cancer, With a Hypothesis Concerning the Role of Androgens and Progesterone In the United States, ovarian cancer is the fourth most frequent cause of cancer death among women, following lung, breast, and colorectal cancers. Each ye... HA Risch - 《Jnci ...
OBJECTIVE: Ovaries of women with polycystic ovary syndrome (PCOS) are typically enlarged and characterized by hyperplastic theca-interstitial tissues producing excessive amounts of androgens. Previously, we have shown that statins decrease theca-interstitial proliferation. We have also presented preliminary ...
In healthy premenopausal women with and without a BRCA mutation we studied (i) estrogen and progesterone levels in saliva over an entire menstrual cycle (n= 20); (ii) cancer-free normal breast-tissue from a control population who had no family or personal history of breast cancer and equiv...
High levels of androgens and/or hypersensitivity of the sebaceous glands to normal androgen levels r... C Dessinioti,CC Zouboulis 被引量: 21发表: 2014年 Local Suppression of Sebum Secretion in Rats by Topical Cyproterone Acetate in Ethanol - ScienceDirect Sebum production was measured on 2 ...
alcohol and smoking are known to increase testosterone levels in women. Heavy drinking has also been reported to promote the conversion of androgens to estrogens. Meanwhile, smoking has been found to cause serious DNA damage, thanks to the chemicals present in tobacco that also disrupt DNA repair...
PCOSis a disorder in which the ovaries, and sometimes the adrenal glands, produce excess amounts of hormones known as androgens. Women with PCOS typically have menstrual irregularities and may have difficulty getting pregnant.Infertility treatmentfor the condition typically involves ovulation induction —...
Gates and colleagues examined the association between use of aspirin, NSAIDs and acetaminophen and concentrations of estrogens and androgens among 740postmenopausal womenwho participated in the Nurses' Health Study. Frequency of all analgesic use was inversely associated with estradiol, free estradiol, est...
During aging, the reduction in DHEA synthesis causes a significant depletion of estrogens and androgens in different organs, such as the ovaries, brain, and liver. Primary Biliary Cholangitis (PBC) is a cholestatic liver disease that begins with immune-mediated bile duct damage, and is followed ...
Sixteen insulin-resistant women with PCOS. Insulin sensitivity (with an IV insulin tolerance test), plasma glucose and insulin levels during an oral glucose tolerance test (OGTT), serum androgens, and lipids were measured at baseline and after each treatment period. Insulin sensitivity, the mean ...
OC68: The use of serum hCG and progesterone measurement to reduce the need for follow‐up of women with pregnancies of unknown location5 alpha-reductaseandrogen receptorandrogensendometriosisgene expressionAbstract:doi:10.1002/uog.4174A. DayKing's College Hospital/Early Pregnancy and Gynaecology ...