BEAM-101 is an investigational cell therapy comprised of autologous CD34+ hematopoietic stem cells that are base edited to introduce A-to-G substitutions into the HBG1/2 gene promoters to disrupt BCL11A binding, leading to increased HbF production. The BEACON Phase 1/2 clinical trial is an ...
RBC count, ×109/μL blood 4.14 (3.94-4.45) 4.22 (3.64-4.58) Hemoglobin, g/dL 132 (127-138) 134 (121-146) Hematocrit, % 0.376 (0.351-0.399) 0.377 (0.338-0.412) White blood cell count, ×103/μL blood 7.93 (5.85-7.75) 5.33 (4.35-6.50) Median (interquartile range) shown, unless...
Iron deficiency is the most common and widespread nutritional disorder worldwide. The automated haematology analyser XN-30 (Sysmex, Kobe, Japan) was developed to detect malaria-infected red blood cells (RBCs) in human blood samples using flow cytometry.
Laboratory tests Anticoagulated EDTA-blood samples were obtained from patients at least once daily until discharge from the ICU. NRBC count was routinely measured in the white cell nucleated (WNR) channel of a Sysmex XN-9000 hema- tology analyzer (Sysmex, Kobe, Japan) using fluorescence flow ...
(B) Overlay histogram of the gated cellular population. The histogram pertains to the cell count and FL. The red and light blue lines indicate Lysercell M- and PBS-treated samples, respectively. (For interpretation of the references to color in this figure legend, the reader is referred to ...
red blood cellsTC-99MRadionuclide ventriculography or Multi Gated Acquisition (MUGA) employing [Tc-99m]Technetium red blood cell (RBC) labeling is considered the gold standard for cardiotoxicity assessments in cancer patients undergoing chemotherapy. This in-vivo RBC labeling technique involves the ...
A 99mTc-red blood cell (RBC)–labeled multigated acquisition is a procedure in which the patient's RBCs are radiolabeled and imaged with electrocardiography-gated cardiac scintigraphy to assess the heart's pumping efficiency. Cold agglutinin disease, or cold antibody autoimmune hemolytic anemia, is ...
Variations in gated blood pool image quality using in vivo, modified in vivo, and in vitro red blood cell labeling techniques. J Nucl Med Techno/1986:14:63-65.Armstrong, L. K.; Ruel, J. M.; Christian, P. E.; Taylor, A. Variation in gated blood-pool image quality using in uiuo,...
7. Influence of corticoids and injection technique on in vivo red blood cell labelling and image quality in multi-gated equilibrium radionuclide ventriculography (RNV)An abstract is unavailable. This article is available as a PDF only.doi:10.1097/00006231-199604000-00122Eising, E....
Described herein is the development of red blood cell membrane-derived microparticles (RBC MPs), which are depleted of hemoglobin (Hb) and express phosphatidylserine on their surface, for the treatment of lung disease. Administration of RBC MPs to the lung via inhalation promotes the production of...