Recurrent major depressive disorder (rMDD) is a relapsing-remitting disease with high morbidity and a 5-year risk of recurrence of up to 80%. This was a prospective pilot study to examine the potential diagnostic and prognostic value of targeted plasma metabolomics in the care of patients with...
But she did not have a period of well-being over the next several years leading up to the current episode of depression. During that several-year period, she probably had mild episodes of major depression each fall and winter, with some sense of clearing in the spring, leading us up to ...
Aim Previous studies consistently reported increased harm avoidance (HA) assessed with the Temperament and Character Inventory (TCI) in patients with major depressive disorder (MDD). However, such findings may have been related with depression severity and number of depressive episodes. The aims of th...
网络中度复发性抑郁障碍 网络释义 1. 中度复发性抑郁障碍 www.scientrans.com|基于 1 个网页
major depressive episode- (psychiatry) a state of depression with all the classic symptoms (anhedonia and lethargy and sleep disturbance and despondency and morbid thoughts and feelings of worthlessness and sometimes attempted suicide) but with no known organic dysfunction ...
Recent studies indicate that patients with first-episode drug-nave (FEDN) and recurrent major depressive disorder (R-MDD) exhibit distinct atrophy patterns in the hippocampal subregions along the proximal-distal axis. However, it remains unclear whether such differences occur along the long axis and ...
The nucleus accumbens (NAc) is considered a hub of reward processing and a growing body of evidence has suggested its crucial role in the pathophysiology of major depressive disorder (MDD). However, inconsistent results have been reported by studies on reward network-focused resting-state functional...
Adults diagnosed with major depressive disorder (MDD) and experiencing a current episode of depression are particularly susceptible to the challenges raised by lockdown, such as disrupted sleep [14], reduced sociability [15] and changes in mood/self-esteem [16]. Therefore, it is important to ...
Patients remained in maintenance therapy for 3 years or until recurrence of a major depressive episode, whichever occurred first. The randomization schedule was generated by the project statistician at the beginning of the trial and given to the research pharmacist. The individual randomization was ...
Objective: The aim of this study is to compare patients who have recurrent and first episode major depressive disorder and healthy controls based upon their childhood traumas. Methods: Sixty subjects with the diagnoses of primarily as major depressive disorder according to DSM-IV-TR who admitted Be...