Locally recurrent rectal cancer (LRRC) is associated with substantial tumor- and treatment-related morbidity. Curative-intent surgical resection is challenging, and when used as a single modality, the results have been poor. Durable local control (LC) and long-term overall survival (OS) may be ...
PURPOSE: After curative surgery for rectal cancer, patients with pelvic recurrence may undergo curative surgical resection. We determined whether salvage s... F Lopez-Kostner,V W Fazio,A Vignali,... - 《Diseases of the Colon & Rectum》 被引量: 281发表: 2001年 Limb salvage surgery for primar...
Advances in surgical practice have helped expand the options for patients with locally recurrent rectal cancer through improvements in reconstructive optio... AH Mirnezami,PM Sagar,D Kavanagh,... - 《Diseases of the Colon & Rectum》 被引量: 90发表: 2010年 The role of surgical management of lo...
Wnt-activating and tumour-promoting roles of SFRP2 have previously been identified in colon and lung cancer, as well as in glioblastoma [47,48,49], and our study suggests a similar role in ovarian cancer. In five ovarian cancer cell lines, SFRP2 did not inhibit WNT signalling and more ...
the anticipated incidence ranges from 1 to 13 percent in different parts of the globe. The recurrence rate of kidney stones is significant. There are effective treatment options, preventative strategies are needed for both new and reoccurring stones to lessen the financial and bodily consequences of...
Dis Colon Rectum. 1963;6297- 300Google ScholarCrossref 35. Shingleton WWParker RTMahaley S Abdominal perfusion for cancer chemotherapy with hypothermia and hyperthermia. Surgery. 1961;50260- 265Google Scholar 36. Wile ASmolin M Hyperthermic pelvic isolation-perfusion in the treatment of refractory ...
et al. Markedly improved outcomes and acceptable toxicity in adolescents and young adults with acute lymphoblastic leukemia following treatment with a pediatric protocol: a phase II study by the Japan Adult Leukemia Study Group. Blood Cancer J. 4, e252 (2014). Article CAS Google Scholar ...
The treatment of advanced cervical cancer consists of platinum-based chemotherapy but, with a response rate of 20% to 30%, is seldom curative and should be considered as palliative treatment. This is reflected in a poor median survival time in these patients; fewer than 20% survive one year ...
Exploration of additional actionable muta- tional events is therefore crucial to refine molecular therapy for this subset of tumors, and to expand treatment options with the potential of improving survival in this devastating disease. The development of targeted therapies in cancer has accelerated the ...
Initial treatment for all patients consisted in parenteral or oral antibiotics, analgesics and bowel rest. In operated individuals, elective resection of the affected colon including the rectosigmoid junction was by laparotomy or laparoscopy. The choice of surgery or continuation of conservative treatment...