Staging rectal cancer with MRI: How to do it, what to look forFerris, N
Magnetic Resonance (MR) imaging is the preferred modality for staging in rectal cancer; however, despite its exceptional soft tissue contrast, segmenting rectal tumors on MR images remains challenging due to the overlapping appearance of tumor and normal tissues, variability in imaging parameters, and...
To enable the evaluation of locoregional disease in the on-going RECTOPET (REctal Cancer Trial on PET/MRI/CT) study; a methodology to match mesorectal imaging findings to histopathology is presented, along with initial observations. FDG-PET/MRI examinati
Local staging and management of rectal cancer has evolved during the past decade. Imaging modalities used for staging rectal cancer include CT, endoscopic ultrasound, pelvic phased-array coil MRI, endorectal MRI, and PET. Each modality has its strengths and limitations. Evidence supports the use o...
Due to current limitations of MRI technology, it is difficult to accurately determine the T-staging of rectal cancer with a single inspection method. Four different methods are typically used to comprehensively determine the T-staging of rectal cancer patients: T1WI, T2WI, ET1WI and DWI. The ...
MRI is the ideal technique for the preoperative staging of these tumours. Aim: To determine the accuracy of local T staging of rectal cancer with MRI, using histopathological staging as the gold. Materials and Methods: Forty consecutive patients admitted with rectal cancer over a period of 18 ...
Complete response prediction in locally advanced rectal cancer (LARC) patients is generally focused on the radiomics analysis of staging MRI. Until now, omics information extracted from gut microbiota and circulating tumor DNA (ctDNA) have not been integrated in composite biomarkers-based models, there...
MRI has become the standard of care for baseline local staging of newly diagnosed rectal adenocarcinomas; as well as evaluation of tumor response to neoadjuvant chemoradiotherapy.2 The current article outlines management of rectal adenocarcinoma, reviews relevant pelvic anatomy along with its clinical impl...
MRI in rectal cancer staging is established, but the role of MRI for the selection of patients for organ-saving treatment is debatable, because MRI is not able to accurately assess tumour response to preoperative chemoradiotherapy (owing to its reliance on morphological changes). Functional MRI is...
Nagtegaal ID, Marijnen CAM (2008) The future of TNM staging in rectal cancer; the era of neoadjuvant therapy. Curr Colorectal Cancer Rep 4:147-154Iris D. Nagtegaal, Corrie A. M. Marijnen. (2008) The future of TNM staging in rectal cancer: The era of neoadjuvant therapy. Current ...