RECOVERY FROM CEREBRO-SPINAL MENINGITIS UNDER INJECTIONS OF COLLARGOL INTO THE SPINAL CANALRECOVERY FROM CEREBRO-SPINAL MENINGITIS UNDER INJECTIONS OF COLLARGOL INTO THE SPINAL CANAL.doi:10.1016/S0140-6736(01)29907-3Muiznieks, Lisa D.Keeley, Fred W....
In the context of spinal cord injury (SCI), infiltrating macrophages assume prominence as the primary inflammatory cells within the lesion core, where the fibrotic scar is predominantly orchestrated by platelet-derived growth factor receptor beta (PDGFRβ+) fibroblasts. Galectin-3, a carbohydrate-bindi...
Steps for transplanting cells The hOM-MSCs preparation (as described above) involves transplanting cells 5 × 107/time, 2 – 3 times over a treatment course of 14 – 21 d. Patients receive intraspinal injections of the transplanted cells, following specific steps: the patient lies on his ...
13 Although similar catheters can be placed for continuous spinal or regional block, the use of epidural catheters is far more common. Intravenous Regional Anesthesia Also known as Bier block, intravenous regional anesthesia (IVRA) is a viable option for superficial procedures involving the knee. ...
Spinal cord injury (SCI) is a debilitating medical condition that can result in the irreversible loss of sensorimotor function. Current therapies fail to provide an effective recovery being crucial to develop more effective approaches. Mesenchymal stem c
Microinjections of Zymosan A into lateral white matter of thoracic spinal cord caused marked activation of Iba1-positive microglia/macrophages and GFAP-positive astrocytes at 3 days post injection in control mice (Supplementary Fig. S1a). These activations were undetectable around a PBS injection ...
Lactate-derived histone lactylation is involved in multiple pathological processes through transcriptional regulation. The role of lactate-derived histone lactylation in the repair of spinal cord injury (SCI) remains unclear. Here we report that overall
Briefly, mice were injected with 10 mg/kg NTG or its vehicle every other day for 8 days (5 i.p. injections total). Two different NTG formulations were tested: first, 5 mg/1.5 ml ampoules and second, 50 mg/50 ml vials (Bioindustria LIM, Novi Liguri, Italy). The 5 ...
Fig. 2: Hyper-IL-6 promotes CST axon regeneration after severe spinal cord crush. a Timeline of surgical interventions for experiments presented in (b–i) and Figs. 3, 4. PTENf/f mice received unilateral injections of AAV2-GFP (PTEN+/+) or AAV2-Cre (PTEN−/−) at P1. After 7...
This surgery is usually performed under general anesthesia, although some patients may be given a spinal or epidural anesthesia. The incision may be horizontal (the "bikini" incision) or a vertical incision from the navel downward. After separating the muscle layers underneath the skin, the ...