Intensive lipid-lowering therapy with atorvastatin 40 or 80 mg, rosuvastatin 20 or 40 mg, simvastatin 80 mg, or statin of any dose + ezetimibe + any statin therapy. † Any statin therapy. ‡ Maximally potent statin (rosuvastatin 20 to 40 mg or atorvastatin 80 mg) at hospital discharge....
up to 400 mg/kg 1 x oral dose:24, 48, 72 h samplingb) [309] −ve for MLA (up to 5000 μg/mlb) andCA (human lymphocytes up to 5000 μg/mlb) [309] +ve rats and mice [309]Non-genotoxic MoA without clinical relevanceb Rosuvastatin(287714-41-4) −ve in standard strains ...