In contrast to the USPSTF recommendations, ACC/AHA clinical guidelines suggest starting statin therapy in adults aged 40 to 75 years old without a history of cardiovascular disease who have an LDL cholesterol level of 70 to 189 mg/dL and a 10-year risk of cardiovascular disease ≥ 7.5%. In...
Guidelines for the use of antiretroviral agents in adults and adolescents with HIV: recommendations for the use of statin therapy as primary prevention of atherosclerotic cardiovascular disease in people with HIV. Updated February 27, 2024. Accessed June 11, 2024. https://clinicalinfo.hiv.gov/en/...
These effects in people without diabetes were supported by a non-randomised study conducted in people with type 2 diabetes and CHD who were placed on statin therapy for 6 weeks [172]. Associated reductions in HbA1c, fasting glucose, triacylglycerols, waist circumference and BMI have also been ...
In more of these updated decision pathways, what are the roles for these new agents? How do we think about the algorithm of who we should be starting these in? Alison Bailey, MD, FACC: The Expert Consensus Decision Pathway just came out, looking at nonstatin therapies. We’re still ...
However, one must take into account that, for example, bosutinib-related diarrhoea may appear as late as 18 months after starting TKI.22 In patients treated with imatinib for least for 3 years, only 72% and 57% of patients were free of nausea and diarrhoea respectively,176 even though ...
Finally, we provide models and methods for generating a human-readable textual critique. The system was successfully evaluated on the test base. Conclusion We show that it is possible to criticize physicians' prescriptions starting from a structured clinical guideline, and to provide clear ...
Before starting any technological activity there must be principle agreement on the development goals to be achieved. Hence, the characteristics of appropriate technology are directly related to and deducted from development theory and practice. It is in this context that one must decide wether or ...
We recommend quantification of proteinuria by protein/creatinine ratio (UPCR) in either a first morning (AM) urine or 24-h urine sample at least once before defining a patient as SRNS and/or starting alternative immunosuppression. We suggest using this baseline value for assessment of subsequent ...
The document also recommends omega-3 fatty acids, particularlyicosapent ethyl (Vascepa, Amarin), on top of statin therapy for patients with hypertriglyceridemia, and calls for lipoprotein(a) to be assessed at least once for all adults. Dia...
The TC and LDL-C goals were achieved by significantly higher percentages of patients prescribed atorvastatin (5133/7928 [64.7%] and 5487/7426 [73.9%], respectively) compared with the rates of patients prescribed any other statin at the recommended starting doses (all, P < 0.05). Conclusions:...