We confirmed that trifluoperazine hydrochloride suppressed human P2X7 responses (IC50 of 6.4 μM). Both paroxetine and trifluoperazine did not inhibit rodent P2X7 responses, and mutation of a known residue (F 95L) did not alter the effect of either drug, suggesting neither drug binds at...
P2X7-specific nanobody into a surface loop of the VP1 capsid protein of AAV2. Such nanobody-displaying recombinant AAV allow 50- to 500-fold stronger transduction of P2X7-expressing cells than the parental AAV. We provide protocols for monitoring the transduction of P2X7-expressing cells by nano...
4-(三氟基)苄溴 98%Recombinant Human C3orf70 proteinRecombinantHumanEphrin-B2价格Smad同源物4检测试盒Anti-RUFY1 antibody Smad同源物6检测试盒Anti-PAPD5 antibody Smad同源物7检测试盒Fluo-4 AM, Fluorescent labeling reagent 嘌呤能受体P2X7检测试盒Coumarin 343 X azide, Blue fluorophore 酪氨激酶受体检测...
Sepsis is a potentially fatal systemic inflammatory response syndrome (SIRS) that threatens millions of lives worldwide.Echinococcus granulosusantigen B (EgAgB) is a protein released by the larvae of the tapeworm. This protein has been shown to play an important role in modulating host immune respo...
Oxygen/glucose deprivation increases the integration of recombinant P2X7 receptors into the plasma membrane of HEK293 cellsApoptosisCationic channelIschemiaPore dilationP2X 7 receptorReceptor traffickingRecombinant human P2X 7 receptors, C-terminally labelled with enhanced green fluorescent protein (P2X 7–...
Donnelly-Roberts DL, Namovic MT, Han P, Jarvis MF (2009) Mammalian P2X7 receptor pharmacology: comparison of recombi- nant mouse, rat and human P2X7 receptors. Br J Pharmacol 157: 1203-1214. doi:10.1111/j.1476-5381.2009.00233.xDonnelly-Roberts DL,Namovic MT,Han P,et al. Mammalian P2X7 ...
Ionic effects on human recombinant P2X7 receptor function. Naunyn Schmiedebergs Arch. Pharmacol. 1999; 359 :102–109.MICHEL, A.D. , CHESSELL, I.P. & HUMPHREY, P.P.A. ( 1999 ). Ionic effects on human recombinant P2X 7 receptor function . Naunyn-Schmiedeberg's Arch. Pharmacol. , 359 ...