Moreover, rhEPO increased the Bcl-2 protein expression levels and decreased the ratio of cleaved caspase-3/caspase-3 in the hippocampus. Finally, rhEPO modulated autophagy in the hippocampus in a time-dependent
The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described,...
**Po0.01 (d) H1975 cells were incubated with 2 U/ml of rhArg for 24 h in the presence or absence of 5 mM NAC and the expression of PARP, cleaved-PARP and cleaved-caspase 3 was measured by western blot analysis depletion. As shown above, ASS and OTC, the synthesizing arginine key ...
Simi- larly, the levels of pro-apoptosis-associated proteins in TBI + rhMFG-E8 group, such as cleaved caspase-3 and Bax, were significantly down-regulated relative to the TBI + Vehicle group, while the expression of pro- survival protein Bcl-2 was up-regulated (Fig. 6a, c–e). After...
Recombinant Human VEGFR1/Flt-1 Fc Chimera Protein Cat # 321-FL (11) Citations (41) Recombinant Mouse ICAM-1/CD54 Fc Chimera Protein, CF Cat # 796-IC (1) Citations (84) Recombinant Human BID (Caspase-8-cleaved) Protein, CF Cat # 882-B8 Citations (8) Mouse VEGFR1/Flt...
APG101 is a human soluble fusion protein consisting of the extracellular domain of CD95 and the Fc portion of IgG1 thereby blocking the interaction of CD95L with its cognate receptor. APG101 was shown to be well tolerated up to high doses in a phase 1 first-in-man study,16 and may ...
Target Species Human Form Liquid Applications Western Blot Clone RM442 Conjugate Unconjugated Gene CASP8 Gene Alias ALPS2B; Apoptotic cysteine protease; apoptotic protease Mch-5; CAP4; CASP8; Casp-8; caspase 8; caspase 8, apoptosis-related cysteine peptidase; caspase 8, apoptosi...
E. coli still remains the most commonly used organism to produce recombinant proteins in research labs. This condition is mirrored by the attention that researchers dedicate to understanding the biology behind protein expression, which is then exploited
RecombinantEndostatin,Human 供应商 Bioworld 产品货号 BK0337 产品报价 ￥询价/100ug 产品说明书 点击查看 购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868 产品新闻 背景资料 Endostatin is a cleaved product of the carboxyl-terminal domain of collagen XVIII. It ...
. A 116 aa propeptide is cleaved intracellularly by the cysteine protease IL-1 beta -converting enzyme (Caspase-1/ICE) to generate the active cytokine. The 17 kDa mature human IL-1 beta shares 96% aa sequence identity with rhesus and 67%-78% with canine, cotton rat, equine, feline, ...