Hong, et. al. EP 0437320, Recombinant DNA and its use in producing human insulin, published Jul. 17, 1991.(Applicant's IDS).EP0437320A1 * 1991年1月4日 1991年7月17日 Korea Institute Of Science And Technology Recombinant DNA and its use in producing human insulin...
Thirty-one previously untreated diabetic individuals received only human insulin (recombinant DNA) for 1 yr with no adverse reactions. The development of serum IgE antibodies to human, porcine, and bovine insulins was assessed by a sepha... P Fireman,SE Fineberg,JA Galloway - 《Diabetes Care》...
A form of DNA produced by combining genetic material from two different sources by means of genetic engineering. Recombinant DNA can be used to change the genetic makeup of a cell, as in adding a gene to make a bacterial cell produce insulin. ...
Human insulin (recombinant DNA) was administered subcutaneously to 16 patients with newly diagnosed insulin-dependent diabetes mellitus (IDDM), whereas a control group of 11 patients received highly purified pork insulin (PPI). The control group was only available for the inpatient period, while the...
Human insulin synthesized from A and B chains separately produced in Escherichia coli from cloned synthetic genes (prepared by the Eli Lilly Research Laboratories, Indianapolis, IN) was characterized by examining its interaction with human cultured lymphocytes, human circulating erythrocytes in vitro, and...
In subject area: Immunology and Microbiology Recombinant technology broadly refers to the molecular cloning of foreign DNA into bacterial extrachromosomal DNA elements (i.e., plasmids) that can be propagated in a bacterial host such as Escherichia coli. ...
More recently, human insulin has become available through both DNA recombinant technology and amino acid substitution techniques. It has proved to have identical characteristics to pork insulin both in vitro and in normal subjects. Clinical ... DPD Home,DKGMM Alberti - 《Drugs》 被引量: 5发表:...
重组DNA技术Recombinant DNA Technology
Cell and Molecualr Biology"; Gerald Karp; 2005 "Molecular Cell Biology"; H. Lodish, et al.; 2000; Chapter 7.1 DNA Cloning with Plasmid Vectors "Molecular Cell Biology"; H. Lodish, et al.; 2000; Glossary Recombinant DNA Iowa Public Television: Recombinant DNA: Example Using Insulin ...
DNA technology is also used to detect the presence of HIV in a person. Application of recombinant DNA technology in Agriculture – For example, manufacture of Bt-Cotton to protect the plant against ball worms. Application of medicines – Insulin production by DNA recombinant technology is a classi...