重组人源化CD3单抗(Recombinant anti-Human CD3 mAb)是在OKT3的基础上,经过人源化改造,并通过基因工程方法生产的T细胞激活性抗体。在保持了OKT3单抗对T细胞激活能力的前提下,最·大·程度上消除了鼠源性抗体的免疫原性。重组人源化CD3单抗识别人TCR ε链,从而激活T细胞活化信号途径,刺激T细胞的活化与增值。 重组人源...
重组人源化CD3单抗(Recombinant anti-Human CD3 mAb)是在OKT3的基础上,经过人源化改造,并通过基因工程方法生产的T细胞激活性抗体。在保持了OKT3单抗对T细胞激活能力的前提下, 最·大·程度上消除了鼠源性抗体的免疫原性。重组人源化CD3单抗识别人TCR ε链,从而激活T细胞活化信号途径,刺激T细胞的活化与增值。 重组人...
抗体名 重组人源化CD3单抗 是否单克隆 克隆性 靶点 见说明书 适应物种 见说明书 形态 见说明书 宿主 见说明书 标记物 包装规格 亚型 见说明书 标识物 见说明书 浓度 见说明书% 免疫原 见说明书 是否进口 GMP-A018 Recombinant anti-Human CD3 mAb Human Cells GMP-A091 Recombinant ...
As early as 1975 the first investigators of this technology recognized the therapeutic and industrial potential of MABs, particularly human monoclonal antibodies (huMABs), yet 18 years later only OKT3 — an anti-T lymphocyte antigen (CD3) murine MAB — is a licensed drug. There are two reasons...
英文名称:Recombinant anti-Human CD52 mAb 产品货号: GMP-A052 产品品牌:近岸蛋白 买试剂,找华雅,更多生物试剂,就在华雅思创 上海华雅思创生物科技有限公司是一家为生命科学领域内的科学研究、细胞 和生物制药相关人员提供 产品和服务的生物高科技公司,干细胞 产品、细胞培养试剂耗材、脐带MSC间充质干细胞培养基、...
Recombinant Human Anti-Human CD3 mAb推荐供应商 我要询价 武汉肽芯生物科技有限公司 联系电话:027-65317797 13667154760 电子邮件:1096814016@qq.com CB指数:58 网址:www.peptidechip.com/ 相关信息:产品目录(10020) 用户评价 英文名称:Recombinant Human Anti-Human CD3 mAb 其它信息:纯度:>=95%;10ug;50ug...
When mouse mAbs are injected into humans, the patients develop anti-mouse mAb antibodies that accelerate their clearance. This human anti-mouse antibody (HAMA) response can occur within a few weeks of the initiation of mAb treatment and precludes long-term therapy. The patients also form immune ...
产品名称:Recombinant anti-Human CD52 mAb重组人源化CD52单抗 产品货号:GMP-A052 产品品牌:近岸蛋白 买试剂,找华雅,更多生物试剂,就在华雅思创 产品介绍: CD52是一种在各种正常和恶性淋巴样细胞上大量(500,000分子/细胞)发现的糖基化的糖基化磷脂酰肌醇(GPI)-锚定的细胞表面蛋白,广泛分布于淋巴细胞...
lactis secreting human pro-insulin (PINS) and IL-10 (LL-PINS+IL-10) to recently-diagnosed diabetic NOD mice [94]. A combination therapy (CT) of LL-PINS+IL-10 with a short-course of subtherapeutic doses anti-CD3 Abs reversed diabetes in 59% of treated mice in comparison to 25% with...
The next generation of mAb-producing cell lines was driven by the problems of hybridoma instability and the development of human anti-mouse antibodies (HAMA) by the patients. Progress in molecular biology techniques and the feasibility of directed genetic manipulation of mammalian cells enabled the pr...