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To address this question, quantitative proteomics was used to compare the sEVs proteome derived from highly metastatic and poorly metastatic lung cancer cells. The proteome data of three biological replicates had good reproducibility, as principal component analysis (PCA) showed that PC2 was 1.5%. ...
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We first estimate model (1) by means of the pooled ordinary least squares (POLS) estimator and the within fixed effects (FE) estimator, bearing in mind that these estimators do not address the Nickell bias14 associated with the presence of the lagged dependent variable as a regressor in mod...
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To address these issues, we used phorbol 12-myristate 13-acetate (PMA) and Ionomycin as reagents for the in vitro assay to mimic inflammation and immune cell response of T cell subsets. 2. Results 2.1. Induction of T cell Differentiation and Cytokine Production Upon PMA/Ionomycin Stimulation ...