The meaning of RECHALLENGE is a physiological or immunological challenge made subsequent to a previous challenge. How to use rechallenge in a sentence.
2002. Successful rechallenge with anti-tumor necrosis factor alpha for psoriatic arthritis after development of demyelinating nervous system disease during initial treatment: comment on the article by Mohan et al. Arthritis Rheum, 46:3107-8; author reply 3108-9....
In summary, CHRONOS demonstrated (to our knowledge for the first time prospectively) that genotyping tumor DNA in the blood can be safely, effectively and conveniently incorporated in the management of patients with mCRC. We conclude that ctDNA analysis is an effective strategy to select patients ...
Rechallenge with lenvatinib showed tumor resensitization. Therefore, rechallenge with lenvatinib may be a treatment option in patients who have experienced progressive disease after initial response to lenvatinib and subsequent sorafenib. 展开 关键词: Differentiated thyroid cancer Tyrosine kinase inhibitor ...
Retreatment with an anti-EGFR monoclonal antibody after prior lines of therapy, including anti-EGFR therapy, may provide an opportunity to shrink the tumor This transcript has been edited for clarity. Anti-EGFR monoclonal antibodies, in particular, cetuximab and panitumumab, are today efficacious treat...
Temodal Brain Tumor Group. J Clin Oncol 17:2762–2771 PubMed CAS Google Scholar Hau P, Koch D, Hundsberger T et al (2007) Safety and feasibility of long-term temozolomide treatment in patients with high-grade glioma. Neurology 68:688–690 Article PubMed CAS Google Scholar Tuettenberg ...
Envafolimab is a single domain anti-PD-L1 inhibitor administered subcutaneously, which can block the PD-1/PD-L1 pathway, reactivate the suppressed T cells to induce anti-tumor immune response and recover the antigen presentation function of DCs [12,13,14]. Envafolimab monotherapy has been pr...
Immune checkpoint inhibitor rechallenge has emerged as a prominent study area in non-small cell lung cancer (NSCLC). β-glucan was reported to reverse resistance to anti-PD-1/PD-L1 inhibitors by regulating the tumor microenvironment. In this self-initiat
The analysis of cfDNA detected the same EGFR activating mutation reported in the tumor tissue in 20/29 patients, with a sensitivity of 69%. Moreover, a p.T790M variant was found in 14/29 patients (48.3%). The median progression-free survival (PFS) was 2.7 months for p.T790M positive ...
It is not easy to decide whether to subject a child with a good prognostic tumor to a drug that has previously caused significant toxicity. One such situation is documented in this report.Keywords: Methotrexate, toxicity关键词:Methotrexate toxicity ...