In large part, this was because early structural and functional studies suggested that ERBB3 had little, if any, intrinsic tyrosine kinase activity and, thus, was unlikely to be an important therapeutic target. Since then, however, numerous publications have demonstrated an important role for ERBB...
TRKA is a transmembrane receptor protein-tyrosine kinase that is stimulated by nerve growth factor and regulates the growth, proliferation, differentiation, and survival of neurons in both the central and peripheral nervous systems. From: Pharmacological Research, 2016 ...
Zhang LD, Gao H, Qin SM, Zeng Q, Chen QF (2022) Osimertinib is an effective epidermal growth factor receptor-tyrosine kinase inhibitor choice for lung cancer with epidermal growth factor receptor exon 18–25 kinase domain duplication: report of two cases. Anticancer Drugs 33(1):e486–e490 Ar...
ErbB3 is a member of the ErbB family of receptor tyrosine kinases. It is unique because it is the only member of the family whose kinase domain is defective. As a result, it is obliged to form heterodimers with other ErbB receptors to signal. In this study, we characterized the ...
Receptor tyrosine kinases (RTKs) play an important role in a variety of cellular processes including growth, motility, differentiation, and metabolism. As such, dysregulation of RTK signaling leads to an assortment of human diseases, most notably, cancer
样本:Receptor tyrosine-protein kinase erbB-2 ELISA Kit 检测方法:详见说明书 应用:ELISA 检测限:0.312-20 ng/mL 货号:BK-F100136 是否进口:是 参数规格 产品名称:Receptor tyrosine-protein kinase erbB-2 ELISA Kit 检测范围:0.312-20 ng/mL 保存条件:2-8℃低温保存 ...
The epidermal growth factor receptor (EGFR) family member erb-b2 receptor tyrosine kinase 2 (ERBB2) is overexpressed in many types of cancers leading to (radio- and chemotherapy) treatment resistance, whereas the underlying mechanisms are still unclear. Autophagy is known to contribute to cancer tr...
HER2/CD340/ERBB2/Receptor Tyrosine-Protein Kinase ErbB-2Human 发布时间:2025/1/14 23:41:35 关注度:462 种 属:Human/Mouse/Rat 标 签:详询 规 格:10ug/50ug/500ug/1mg 缓 冲 液:0.01mol/L的PBS、pH:7.2、0.2%Procline-300。 表达宿主:E.coli/Cells 内毒素:经LAL检测验证,小于0.1ng/ul(0.1EU...
中文名称:Recombinant Rat Receptor tyrosine-protein kinase ErbB-2 Protein英文名称:Recombinant Rat Receptor tyrosine-protein kinase ErbB-2 Protein 品牌:沪震生物产地:中国/上海 保存条件:-20°C纯度规格:> 99% 产品类别:重组蛋白 货号:HZ505116TP用途范围:Positive Control; Immunogen; SDS-PAGE; WB ...
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