We previously reported that receptor activator of NF-κB ligand (RANKL) specifically facilitates head and neck squamous cell carcinoma (HNSCC) progressionin vivo. Here, we report a novel role for RANKL in the regulation of cell adhesion. Among the major type I collagen receptors, integrin α2 ...
Receptor activator of NF-kappaB ligand (RANKL); antisense agents; drug screening; kitsdoi:US7700574 B2Compounds, compositions and methods are provided for modulating the expression of RANKL. The compositions comprise oligonucleotides, targeted to nucleic acid encoding RANKL. Methods of using these ...
Receptor Activator of NF-κB Ligand (RANKL), a mem- ber of the TNF family, is a protein normally expressed on the surface of stromal cells and osteoblasts, and mediates osteoclast differentiation and osteolytic bone resorption [20, 21]. Physiologically, RANKL binds RANK receptor on the surface...
6) ligand of receptor activator of NF-kB(RANKL) 核因子活化因子受体配体补充资料:正常人白细胞转移因子 , 白细胞转移因子,转移因子 药物名称:转移因子英文名:Transfer Factor别名: 正常人白细胞转移因子 , 白细胞转移因子,转移因子外文名:Transfer Factor ,TF适应症: 为细胞免疫反应增强剂,能将细胞免疫活性...
许多研究认为,骨代谢调控因子主要通过调节OB表达核因子κB受体活化因子配体(receptor activator of NF-κB ligand,RANKL)及骨保护素(osteoprotegerin,OPG),从而间接调控OC的形成及骨吸收功能。 2. To investigate the expression of RANKL,OPG and RANKL mRNA,OPG mRNA, osteobalsts obtained from Sprague Dawley rats...
Ligand 英['lɪg(ə)nd] 美 ['laɪgənd] 释义 n. (生化)配位体,配基 例句 better drugs will be designed once more is understood about receptor-ligand interactions and more information about targets is available from high-resolution studies of their properties in solution.一旦对受体-配体...
The receptor activator of NF-kappaB (RANK) and its ligand RANKL are key molecules for differentiation and activation of osteoclasts. RANKL stimulates transcription factors AP-1 through mitogen-activated protein kinase (MAPK) activation, and NF-kappaB through IkappaB kinase (IKK) activation. Tumor nec...
receptor activator of nf-b ligand induction via jak2 and stat5a in mammary epithelial cells* Receptor Activator of NF-κB Ligand Induction via Jak2 and Stat5a in Mammary Epithelial CellsCerebral amyloid angiopathy (CAA) due to β-amyloid (Aβ) ... S Srivastava,M Matsuda,Z Hou,... 被引量...
MURINE SOLUBLE RECEPTOR ACTIVATOR OF NFKB LIGAND MURINE ODF MURINE OPGL MURINE OSTEOCLAST DIFFERENTIATION FACTOR MURINE OSTEOPROTEGERIN LIGAND MURINE SRANKL MURINE TNF-RELATED ACTIVATION-INDUCED CYTOKINE MURINE TNFSF11
3) receptor activator of nuclear factor kappa B ligand(RANKL) 核因子kB受体激活物配体4) Receptor activator of NF-КB ligand(RANKL) 核因子-КB受体活化配体5) Receptor activator of nuclear factor-κB ligand 核因子-κB受体激活剂配基6) receptor activator of nuclear factor-κB ligand 核因子...