This chapter examines a number of myths and misconceptions about recent evolution of humans, focusing primarily on the last 12,000 years. It also examines a number of myths and misconceptions about human variation, a topic that is best understood in terms of past evolutionary events. The chapter...
Therefore, I discuss how patterns and processes associated with sex linkage in male- and female-heterogametic systems offer a useful contrast in the study of sex-chromosome evolution. 展开 关键词: Animals Humans Mice Evolution, Molecular Genetic Heterogeneity Mutation Sex Determination Processes Plants...
We therefore employed a multi-disciplinary approach to test the role of 370A in recent human evolution. This included modeling to reconstruct the evolutionary history of 370A, and a knockin mouse model to examine its direct phenotypic consequences. Analysis of the mouse knockin revealed phenotypes ...
Background and Objectives: Analysis of positively-selected genes can help us understand how human evolved, especially the evolution of highly developed cognitive functions. However, previous works have reached conflicting conclusions regarding whether human neuronal genes are over-represented among genes unde...
The neutral theory of molecular evolution in the genomic era. Annu. Rev. Genomics Hum. Genet. 11, 265–289 (2010). Article CAS PubMed Google Scholar Schrempf, D. & Szöllösi, G. in Phylogenetics in the Genomic Era (eds Scornavacca, C. et al.) 3:1:1–3.1:23 (HAL Open ...
The defining process in the evolution of primates and particularly humans is the dramatic expansion of the brain. While many types of genes could potential... PD Evans,JR Anderson,EJ Vallender,... - 《Human Molecular Genetics》 被引量: 321发表: 2004年 Colloquium paper: reconstructing human evo...
Timeline demonstrating evolution in the treatment regimen for PC Full size image This review intends to provide an overview of PC, considering aspects such as the risk factors, clinical representations, different methods of diagnosis, treatment, and management, and the QoL of patients with PC. As ...
Unfortunately, rat genetics have been lagging behind (compared to the mouse), but in the last decade considerable progress has been made in the field of "rat genomics," as will be briefly reviewed below.关键词: Humans APACHE Retrospective Studies Parenteral Nutrition Intensive Care Units Practice ...
T. et al. Cis-regulatory changes in Kit ligand expression and parallel evolution of pigmentation in sticklebacks and humans. Cell 131, 1179–1189 (2007). Article CAS PubMed PubMed Central Google Scholar Sulem, P. et al. Genetic determinants of hair, eye and skin pigmentation in Europeans....
Evolutionary geography is used to explore two events: the evolution of the Neanderthal lineage and the relationship between an ancestral bottleneck with the evolution of anatomically modern humans and their diversity. We argue that the Neanderthal and modern lineages share a common ancestor in an ...