Many natural flavonoids and their synthetic analogs are being investigated for their potential applications in anticancer therapies, because of their multi-targeted mechanism of action. Thus, the aim of the present chapter is to highlight the new insights on the recent progress of flavonoids as ...
there is an ongoing and pressing need for the development of new cancer drugs. Natural compounds and their semi-synthetic derivatives continue to show promise as potential therapeutic leads, due to their high chemical diversity, biochemical
including anticancer [21], anti-inflammatory [22], antioxidant [23], and immunomodulatory actions [24]. Numerous investigations have documented the extensive utilization of natural products in the treatment
Cerebral ischemia, also known as cerebral ischemic stroke or cerebrovascular ischemia, is the most common type of stroke (>80%) and is the second leading cause of death, dementia, and disability worldwide.1This condition occurs when a sudden obstruction of the blood supply or a reduction of n...
Because of potent anticancer activity of mycoepoxydiene (12), the culture conditions for the production of 12 by Phomopsis sp. were optimized, leading to the final yield of 354 mg/L [9]. Recently, mycoepoxydiene (12) was found to exhibit interesting biological activities, for example, ...
Flavonoids as Anticancer Agents: Recent Progress and State of the Art?. Estelle Genoux,Edwige Nicolle,Ahcene Boumendjel. CURRENT ORGANIC CHEMISTRY . 2011Genoux, E., Nicolle, E., & Boumendjel, A. (2011). Flavonoids as anticancer agents: Recent progress and state of the art? Current Organic...
Xu, "Recent advance in the research of flavonoids as anticancer agents," Mini-Reviews in Medicinal Chemistry, vol. 7, no. 7, pp. 663-678, 2007.Li Y, Fang H, Xu W. Recent advance in the research of flavonoids as anticancer agents. Mini Rev Med Chem. 2007; 7(7):663-78...
Flavonoids as Anticancer Agents: Recent Progress and State of the Art?. Estelle Genoux,Edwige Nicolle,Ahcene Boumendjel. CURRENT ORGANIC CHEMISTRY . 2011Genoux, E., Nicolle, E., & Boumendjel, A. (2011). Flavonoids as anticancer agents: Recent progress and state of the art? Current Organic...
[195]. Additionally, grape seed proanthocyanidin reduces inflammation and reverses pulmonary vascular remodeling in monocrotaline-induced pulmonary arterial hypertension [196,197]. Such discoveries provide a theoretical basis and new perspectives for researchers to explore the treatment of pulmonary hypertension...
The present chapter summarizes the purported cellular, molecular, and genetic mechanisms of anticancer action of flavonoids, such as apoptosis induction, cell cycle arrest, anti-angiogenesis, anti-metastasis, and anti-inflammatory and antioxidant aspects. In addition, the anticancer roles of related ...