influencing daily life. These chronic or episodic disorders can result in despondency, apathy, remorse, difficulty sleeping, fatigue, and inattention. Anxiety disorders, such as generalized anxiety disorder, panic disorder, phobias, social anxiety disorder, obsessive–compulsive disorder (OCD)...
The last quarter century has witnessed fundamental discoveries and prominent advances in protein and lipid kinase function and inhibition. The FDA approval of the Bcr-Abl inhibitor imatinib in 2001 and subsequent clinical successes in the treatment of chronic myeloid leukemia (CML) marked the emergence...