Two of the new compounds belong to the new group of siRNAs and are being investigated for use in thromboprotection and HAE treatment. ALN-F12 targets a 23-nucleotide region of FXII mRNA and is still in preclinical development. In a study in mice on the prevention of thrombosis, a decrease...
Besides, baicalein inhibited the morphological changes and migratory activity of MDA-MB-231 cells induced by laminin-332 (LN-332)[151]. In vivo experiments showed that baicalein significantly inhibited tumor growth and metastasis[55]. In G protein-coupled estrogen receptor (GPR30)-positive breast ...
Changes in gene expressions related to cellular stress and chemoattractant using a co-culture system (6- well insert plate system) of human liver cancer HuH-7 cells and human promyelocytic leukemia HL-60 cells, which had undergone terminal differentiation induced by 16 nM TPA, were reported in ...
The Eurasian Steppe belt is one of the largest biomes in the Northern Hemisphere. We provide here a range-wide phylogeography of the flightless steppe beetle Lethrus apterus that inhabits the western part of the Steppe belt through the study of populatio
Everyone knows the world has changed and at Strike Adventure we've noticed big economic changes over the past decade. Full-time guides have had to broaden their fishing base to appeal to a wider range of anglers and our marine fishing adventures have been lots of fun. We've made some grea...
2012 Single amino acid modification of adeno-associated virus capsid changes transduction and humoral immune profiles. J. Virol. 86 7752–7759 Article CAS PubMed PubMed Central Google Scholar Liu D, Zhu M, Zhang Y, et al. 2021 Crossing the blood-brain barrier with AAV vectors. Metab. ...
in biosensors, drug delivery, and tissue engineering/regenerative medicine for the diagnosis and/or treatment of NDDs. The development of 2D material-based biosensors has enabled the early detection and monitoring of NDDs via the precise detection of biomarkers or biological changes, while 2D material...
In bifocal metalenses, the focal distance increases when the phase of GST changes from amorphous to crystalline (Yin et al., 2017) as a result of a difference in the plasmonic resonances of the two phases (Figure 3B). A duplex focusing metalens using VO2 has been demonstrated as a ...
Astaxanthin production has relied mostly on most microalgal strains, such asChlorella zofingiensis,Haematococcus pluvialis, andScenedesmus obliquus. Generally, no obvious morphological changes are observed during the cultivation of green-colored microalgae (Ranjbar et al.2008). Under adverse conditions, th...
[97,98,99]. By appropriate thermal, optical, or electrical stimulus, GST can be repeatedly switched between amorphous and crystalline states and exhibit different refractive index with high contrast in the near- and middle-infrared spectral range. Combining plasmonic metasurfaces with GST, switchable...