With breakthroughs in cell isolation and sequencing technologies, single-cell RNA sequencing (scRNA-seq) has enabled unbiased genome-wide profiling of many cells at the single-cell level in a single run. scRNA-seq has been used to analyse the transcriptomics of individual cells, which helps ...
This article critically evaluates recent breakthroughs, addresses the current challenges faced by researchers, and explores the future directions of topical and transdermal approaches in melanoma management. By presenting a summary of the latest research and predicting future trends, this review aims to ...
The rapid development of genome editing technology has brought major breakthroughs in the fields of life science and medicine. In recent years, the clustered regularly interspaced short palindromic repeats (CRISPR)-based genome editing toolbox has been greatly expanded, not only with emerging CRISPR-as...
Nanotechnology breakthroughs have made it possible to deliver drugs effectively and precisely to the tumor site, with less toxicity. Also, administration of multimodal therapeutic regimes and innovative theranostic platforms with personalized treatment are some of the many great promises of nanomedicine. ...
practitioners, and scholars within the fields of Nanomedicine and Nanotechnology. Its commitment to open access and rigorous peer review ensures that the latest breakthroughs and discoveries are made accessible to a global audience, catalyzing progress and innovation within this dynamic and rapidly evolving...
's transformational influence in surgical applications and its promise for future breakthroughs. Graphical Abstract Introduction The operating room is one of the most stressful parts of the hospital, and nanotechnology has entered the operating room environment such as any other environment and is ...
Recent advances in reinforcement learning have led to significant breakthroughs in game playing, robotics, and resource management. AlphaGo's victory over a world champion Go player marked a landmark achievement, showcasing the potential of reinforcement learning to tackle complex problems. Furthermore,...
At present, breakthroughs have been made in targeting homologous recombination defects as a new and effective therapeutic measure for TNBC, with platinum analogs and PARP inhibitors achieving considerable results even in the metastatic setting. In androgen receptor-positive TNBC, AR inhibitors and key ...
Nanotechnology research, AI-driven welding optimization, sustainability, recycling, and environmentally friendly joining techniques are some of the future directions in this field. It is anticipated that these technologies will result in important industrial breakthroughs in the automotive, aerospace, and ...
In recent years, breakthroughs in covalent inhibitors discovered through electrophile-first approaches made it possible to target KRASG12C mutants.50 Cysteine is located at codon 12 of KRASG12C, making it possible to selectively target mutant KRAS covalently. Importantly, KRAS active sites lack cyste...