This comprehensive review explores the intricate landscape of lung cancer research, delving into recent breakthroughs and their implications for diagnosis, therapy, and prevention. Genomic profiling and biomarker identification have ushered in the era of personalised medicine, enabling targeted therapies that...
Lung cancer, a multifaceted disease, demands tailored therapeutic approaches due to its diverse subtypes and stages. This comprehensive review explores the intricate landscape of lung cancer research, delving into recent breakthroughs and their implications for diagnosis, therapy, and prevention. Genomic pr...
Recent breakthroughs in cancer therapy have shown a progressive trend away from monotherapy and toward various therapeutic techniques such as synergistic bimodal and trimodal cancer therapies within a single system [3]. Outstanding advantages of nanomaterials have contributed to rapid nanotechnological develop...
Lung cancer continues to be the leading cause of cancer-related death worldwide. In the last decade, significant advancements in the diagnosis and treatment of lung cancer, particularly NSCLC, have been achieved with the help of molecular translational research. Among the hopeful breakthroughs in the...
In recent years, breakthroughs in covalent inhibitors discovered through electrophile-first approaches made it possible to target KRASG12C mutants.50 Cysteine is located at codon 12 of KRASG12C, making it possible to selectively target mutant KRAS covalently. Importantly, KRAS active sites lack cyste...
Cancer is a kind of serious disease that threatens the health and life of human beings [1]. The strategies for tumor therapy mainly include surgical resection, chemotherapy, and radiation therapy in clinical practice. Although these methods effectively inhibit tumor growth, improve the quality of li...
explain the principles of CRISPR/Cas9 genome editing technology and introduce CRISPR as a tool in tumor modeling. We next focus on the CRISPR screening for target discovery that reveals tumorigenesis, immune evasion, and drug resistance mechanisms. Moreover, we discuss the recent breakthroughs of gen...
Advances in probiotics research: mechanisms of action, health benefits, and limitations in applications Recent breakthroughs in the identification of potent probiotic strains and their prospective applications in biomedical research are delineated. Comprehensive ... P Karan,B Krithika,Prajapati HarshPrajapati...
practitioners, and scholars within the fields of Nanomedicine and Nanotechnology. Its commitment to open access and rigorous peer review ensures that the latest breakthroughs and discoveries are made accessible to a global audience, catalyzing progress and innovation within this dynamic and rapidly evolving...
providing approaches to developing multi-functional drug delivery systems (DDSs). In this review, we first describe the principle of labeling cells or pathogenic microorganisms with bioorthogonal groups. We then highlight recent breakthroughs in developing active targeting DDSs to tumors, immune systems,...