E. 2015. Recent Breakthrough in the Biology of Astaxanthin Accumulation by Microalagal Cell. Photosynthesis Research, 125: 437-449Solovchenko, A. E. (2015). Recent breakthroughs in the biology of astaxanthin accumulation by microalgal cell. Photosynth. Res. 125, 437-449. doi: 10.1007/s11120...
Five breakthroughs of the past decade The 13 ENBDC committee members quickly reached a consensus on the greatest breakthroughs of the last decade. While some implicit bias cannot be excluded, there was unanimous agreement that the development and application of new technologies, in combination with k...
In recent years, breakthroughs in covalent inhibitors discovered through electrophile-first approaches made it possible to target KRASG12C mutants.50 Cysteine is located at codon 12 of KRASG12C, making it possible to selectively target mutant KRAS covalently. Importantly, KRAS active sites lack cyste...
While instrumentation advancements have allowed re- cent breakthroughs in structural biology of amyloids, there are still major fundamental challenges to solve. For example, what are the molecular factors that determine the convergence toward a given strain/structure? How can one reproduce the brain-...
Their potential impact on RNA biology allows these structures to shape cellular processes relevant to disease development, making their targeting for therapeutic purposes an attractive option. We review here the current knowledge on RG4s, focusing on the latest breakthroughs supporting the notion of ...
(A) Overview of aquaporin structural biology. Water molecules (red spheres) traverse the pore in single file. Two key regions facilitate water transport capacity [Asn-Pro-Ala (NPA) motifs, green], and solute exclusion (ar/R selectivity filter, red). For some isoforms, small neutral solutes ...
providing approaches to developing multi-functional drug delivery systems (DDSs). In this review, we first describe the principle of labeling cells or pathogenic microorganisms with bioorthogonal groups. We then highlight recent breakthroughs in developing active targeting DDSs to tumors, immune systems,...
BLeaf-cutting ants and their fungus farms are a marvel of nature and perhaps the best known example of symbiosis, the mutual dependence of two species. The ants’achievement is remarkable --the biologist Edward O. Wilson has called it “one of the major breakthroughs in animal evolution”--...
Nanotechnology breakthroughs have made it possible to deliver drugs effectively and precisely to the tumor site, with less toxicity. Also, administration of multimodal therapeutic regimes and innovative theranostic platforms with personalized treatment are some of the many great promises of nanomedicine. ...
The combined influence of new computational tools and techniques with an increase of massive data sets transforms many research fields and can lead to technological breakthroughs that billions of people can make use of it. The past few years have seen re