D. et al. Clinical and biological correlates of neurotoxicity associated with CAR T-cell therapy in patients with B-cell acute lymphoblastic leukemia. Cancer Discov. 8, 958–971 (2018). This paper shows that neurotoxicity is correlated with levels of pro-inflammatory cytokines in the CSF. CAS ...
Although this trial has demonstrated the safety usage of modified MSCs, it is nevertheless important to execute caution since the biological properties of MSC in the tumor microenvironment have been complicated by the limited lineage-specific markers and the inter- and intra-clonal heterogeneity of MSC...
Carison R M K, Tatddni C & Djerassi C. Biological implications of recent discoveries in the marine sterol field, (Ananchenko S N, cd. ) Frontiers of bioo~amr chemtstr.v and molecular biolog~. New York: Pergamon Press, 1980. p, 211-24....
The plant gene’s smaller size and simpler biological requirements enhance its functionality for diverse applications. The smaller gene plays a vital role, acting as a bridge between plant metabolism (新陈代谢) and light production. This connection allows the plant’s inner dynamics to be ...
biological processes at the protein level. Over the past decade, we have witnessed great expansion of knowledge of human diseases with the application of MS-based proteomic technologies, which has led to many exciting discoveries. Herein we review the recent progress in MS-based proteomics in ...
Some of these discoveries removed dogmas that prevailed in the literature for many decades. These are not only fascinating for the chemists interested in mechanisms but also teach us how such difficult chemistry can be done. 展开 DOI: 10.1016/S1367-5931(01)00018-7 年份: 2001 ...
Historical timeline of essential discoveries in fundamental molecular biology theory and critical developments in NADs therapy. The orange boxes represent major biological discoveries in nucleic acids development, including the discovery of DNA and RNA, as well as researchers’ exploration of special biologi...
Nanomedicines scope is extensive, spanning from the practical implementation of nanomaterials and biological devices in the medical arena to the potential implications of nanoelectronics biosensors and the promising avenues presented by molecular nanotechnology. JRANN recognizes itself as an optimal platform fo...
Protein–protein interactions (PPIs) and their networks are of great significance in biological processes and in the regulation of the cell cycle, offering another potential avenue for treatments of complex diseases. RAS and TFs such as p53 and Myc are also subjected to PPI networks. A portion ...
Anaerobic ammonium oxidation (anammox) processes are gaining attention owing to their advantages over the conventional biological nitrogen removal processes. Although technologies related to sidestream anammox processes are being adopted as the latest advanced solutions, the application of these processes to ...