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The density and spatial distribution of GABAergic neurons, labelled using calcium binding proteins, in the anterior cingulate cortex in major depressive disorder, bipolar disorder, and schizophrenia. Biol Psychiatry 2002; 51: 377–386. Article CAS PubMed Google Scholar Uranova NA, Vostrikov VM, ...
Although several review articles on epigenetics of obesity have been published in recent years [5,8,9,17,18,19], these published papers often include only one or two mechanisms of epigenetics of obesity. There are still few systematic and comprehensive review papers in this field. Therefore, th...
Multiple lines of evidence suggest that the dorsolateral prefrontal cortex (DLPFC) is abnormal in schizophrenia (SZ). Behaviorally, it is well established that cognitive processes associated with the region are impaired in SZ, such as cognitive control and working memory [22], [31]. Neuroimaging ...
in which a 23-year-old male patient with a history of schizophrenia was initiated on risperidone treatment at slowly increasing doses for acute psychosis [147]. The patient was noted to have a rise in ALT and AST from 25 U/L and 23 U/L on day 1 to 469 U/L and 125 U/L, ...
The CNTNAP2 gene has recently been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome [58], schizophrenia [59], epilepsy [59, 60], autism [57, 61–65], ADHD [66] and mental retardation [45] (Table 1). This diverse range of studies provides eviden...
The primary basis for our view that schizophrenia is a genetic morphism is the fact that it clearly has a strong genetic component, and that its incidence is more than 1 per cent, a figure too high to be maintained by mutation alone. . 1965 Nature Publishing Group...
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience. Abstract The pathophysiology of psychotic and other symptoms in schizophrenia remains a mystery despite decades of research. Even ...
Neurological disorders affect various aspects of life. Finding drugs for the central nervous system is a very challenging and complex task due to the invol
K. Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia. Nat. Rev. Drug Discov. 3, 353–359 (2004). CAS PubMed Google Scholar Alexandrov, V., Brunner, D., Hanania, T. & Leahy, E. High-throughput analysis of behavior for drug ...