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4c). The nitrogen atom on the pyridine ring forms a potential hydrogen bond with S1132P1 (Fig. 4d). The nitrogen atom on 9-nitrophenyl and the oxygen atom on 5-dicarboxylic acid of the pyridine ring form hydrogen bonds with T1056S5III and Q1060S5III, respectively (Fig. 4d). Whereas ...
Samples were processed using S-trap micro-spin columns according to the manufacturer’s instructions, with reduction and alkylation being performed with 40 mM chloroacetamide (Sigma) and 10 mM tri(2-carboxyethyl)phosphine hydrochloride (BondBreaker, Thermo Fisher). Protein digestion was performed ...
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Previously, several protein-coding tumor suppressors localized at 1p36 have been reported. In the present work, we focus on functional long non-coding RNAs (lncRNAs) embedded in this locus. Small interfering RNA was used to identify lncRNA candidates wit