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Chronic inflammation in the etiology of disease across the life span David Furman, Judith Campisi, Eric Verdin … (2019) Although intermittent increases in inflammation are critical for survival during physical injury and infection, recent research has revealed that certain social, environmental and life...
Epidemiologic studies have identified a positive association between obesity and colorectal neoplasia. Adiposity induces systemic low-grade inflammation, which is commonly assessed with a sensitive biomarker, C-reactive protein (CRP). To understand the molecular mechanisms of obesity in the etiology of col...
The etiology and pathogenesis of Crohn's disease (CD) are likely varied and differ across the diverse presentations of this heterogeneous condition.The authors, with their extensive experience, offer a critique of this situation. Crucial elements of diagnostic and surgical management procedures for the...
version of the two isomers indicates the loss of one deuterium (Table 1), meaning the A ring is hydroxylated (at position 2 or 4) and involved in both metabolites, forming 2-OH-E2 and 4-OH-E2. E2 can also form E1, and therefore many hydroxylated metabolites found in E1 incubations ...