The majority of olefin-forming reactions of synthetic importance are beta eliminations, which usually involve the removal of the elements HX, from the adjacent carbon atoms. The processes are often base-catalyzed but will also occur in the absence of bases under solvolytic conditions. The ...
Baylis–Hillman reaction and aza〣aylis–Hillman reaction importance of synthetic applicationsThis chapter reviews mechanisms and energetics for Brnsted-acid-catalysed glucose condensations, dehydration, and isomerization reactions. It discusses the recent developments in the asymmetric synthesis of spiroketals...
This review will give an overview of the current progress of the famous CuAAC-(Click)-reaction, including postulated mechanisms and importance of additives. It will sum up the challenges that have been mastered under critical consideration of the fulfillment of the original Click-criteria.Keywords:...
Recent progress in synthetic methods and structure determination has resulted in several new developments in the chemistry of glycosyl azides. A review on these synthetically useful intermediates was published by Micheel and Klemer1 more than 30 years ago but newer treatments2,3 of related topics ...
Recognition of Belousov-Zhabotinsky-type oscillations in autosynthetic micropyretic reactions Journal International Journal of Self-Propagating High-Temperature Synthesis Volume 18, Issue 4 , pp 219-234 Cover Date 2009-12-01 DOI 10.3103/S1061386209040013 Print ISSN 1061-3862 Online ISSN 1934-788X Pu...
Hybrid fused two-dimensional/three-dimensional (2D/3D) rings are important pharmacophores in drugs owing to their unique structural and physicochemical properties. Preparation of these strained ring systems often requires elaborate synthetic effort and e
(Novotny et al.2009). Chloride retention in a metropolitan region of Canada ranged from 40–90% and was related to urban land use patterns (Oswald et al.2019). A growing body of work supports the growing importance of quantifying salt storage and retention within soils and groundwater in ...
We also demonstrate similar improvements in the mapping of reactions from which “synthetic rules” were previously extracted (often incorrectly, as it turns out) and were used as the basis for synthetic design algorithms. Accurate and general-scope mapping algorithms like the one we describe are ...
Still, for a whole century the chemistry of isocyanides remained rather a neglected part of organic chemistry with only 12 isocyanides prepared and just a few of their reactions introduced [1]. In that period reactions of isocyanides of particular importance were the formation of tetrazole ...
High-throughput screening for optimal reaction conditions and the search for efficient catalysts is of eminent importance in the development of chemical processes and for expanding the spectrum of synthetic methodologies in chemistry. In this context we report a novel approach for a microfluidic chemical...