Reaction Control in Fungal Fatty Acid SynthaseNot Availabledoi:10.1016/j.bpj.2012.11.3675Buelens, FlorisGrininger, MartinGrubmüller, HelmutElsevier Inc.Biophysical Journal
Inhibitory Effects of Flavonoids on Animal Fatty Acid Synthase The inhibitory effects of 15 flavonoids on animal fatty acid synthase (FAS, EC 2.3.1.85) were investigated, and 9 of them were found to inhibit FAS with IC... BH Li,WX Tian - 《Journal of Biochemistry》 被引量: 120发表: 2004...
Rational pathway engineering of type I fatty acid synthase allows the biosynthesis of triacetic acid lactone from D-glucose in vivo. Metabolic pathway engineering is a powerful tool to synthesize structurally diverse and complex chemicals via genetic manipulation of multistep catalytic s... W Zha,Z ...
(1985). Elementary steps in the reaction mech- anism of chicken liver fatty acid synthase. Acylation of specific binding sites. J. Biol. Chem. 260, 13532-13538.ZY Yuan,and GG Hammes.Elementary steps in the reaction mechanism of chicken liver fatty acid synthase. Acylation of specific ...
The distribution of fatty acids showed a decrease in tetradecanoic (14:0), palmitic/oleic (16:0/18:1) and tuberculostearic (18:0-10Me) acids, with increases in stearic (18:0) and longer-chain fatty acids, consistent with inhibition of the Fatty Acid Synthase type II (ref. 32) (FASII...
Adenosylcobalamin (AdoCbl), a biologically active form of vitamin B12 (coenzyme B12), is one of the most complex metal-containing natural compounds and an essential vitamin for animals. However, AdoCbl can only be de novo synthesized by prokaryotes, and
The key enzymes in citric acid cycle include A、isocitrate dehydrogenase B、malate dehydrogenase C、α - ketoglutarate dehydrogenase complex D、citrate synthase 点击查看答案 第9题 Metabolic processes that occur in cytosol and mitochondria are A、citric acid cycle B、gluconeogenesis C、urea synthesis D...
the fungal 18S ribosomal gene in 95per cent for the samples. These results suggest that the enhanced DNA removal technique demonstrates much better performance for gDNA removal from complex samples such as HM.Insulin is a hormone created by β-cells of the pancreas and controls the actual quantit...
The work presented here describes the three-dimensional structure of the tetrameric biosynthetic thiolase from Z. ramigera in complex with a reaction intermediate at 2.0 Å resolution. The enzyme has the same overall fold as the β-ketoacyl carrier protein synthase II [24], and the dimeric per...
Two prominent examples are isopenicillin N synthase (IPNS) (6, 7) and 1-aminocyclopropane-1-carboxylic acid (ACC) oxidase (ACCO), the latter of which catalyzes the biosynthesis of the plant hormone ethylene (Fig. 1A) (8, 9), which regulates processes including fruit ripening and senescence ...