蛋白描述: regulator of chromosome condensation isoform a [Homo sapiens] 蛋白大小: 452 aa 蛋白序列: MSPKRIAKRRSPPADAIPKSKKVKDTRAAASRRVPGARSCQGACGPSPPDQKTRPVSHRS HSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPEDVVQAEAGGMHTVCLSKSGQVY SFGCNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGSFRDN NGVIGLLEPM...
Apart from a recently described isoform which predominates in the inner segments of retinal cones and whose RLD is slightly truncated [11], the two main RPGR isoforms seem to be RPGRex1–19 and RPGRORF15. Both share the same RLD but differ in their C-termini, where RPGRORF15 has a ...
4d, e). As expected, the interaction of RCC1 with either isoform was completely disrupted by a dual point mutation at P2/P2′. Unlike the full-length RCC1, the isolated RCC1 NLS bound either importin α isoform with high affinity and this interaction was reduced, but not completely ...
Identification of a novel mouse GDP dissociation inhibitor isoform and two other potential partners of Rab6 J. Biol. Chem., 270 (1995), pp. 14801-14808 View PDFView articleView in ScopusGoogle Scholar Jantsch-Plunger et al. 2000 V. Jantsch-Plunger, P. Gonczy, A. Romano, H. Schnabel,...
Histone deacetylase inhibitor (HDACi) is a group of epigenetic modulators, including HDAC isoform-selective inhibitors (e.g. Entinostat, Romidepsin, Trapoxin A, and Valproic acid) and against all types of HDACs (pan-inhibitors, e.g. Trichostatin A, Vorinostat, Panobinostat, Belinostat, and Praci...
This pathway is dependent upon both a preexisting Ran gradient and energy, and preferentially uses the importin-alpha3 isoform of importin-alpha. The second pathway is not mediated by the NTD of RCC1. This novel pathway does not require importin-alpha or importin-beta or the addition of any...