RAW-Lucia™ ISG Cells RAW-Lucia™ ISG cells were generated from the murine RAW 264.7 macrophage cell line by stable integration of an interferon regulatory factor (IRF)-inducible Lucia luciferase reporter construct. RAW 264.7 have been reported to express IFI16 [1], DDX41 and AIM2 [2]....
RAW-Lucia™ ISG-KO-IRF5 Cells IRF5 knockout IRF-inducible Lucia luciferase reporter mouse macrophages Catalog code: rawl-koirf5 https://www.invivogen.com/raw-lucia-isg-ko-irf5 For research use only Version 23A06-MM PRODUCT INFORMATION Contents and Storage • 3-7 x 106 of RAW-...
RAW-Lucia™ ISG-KO-IRF5 cells were generated from the mouse RAW-Lucia™ ISG macrophage cell line by stable knockout of the interferon regulatory factor 5 (IRF5) gene. These cells feature an inducible reporter allowing the study of IRF pathways by mon
RAW-Lucia™ ISG-KO-MAVS and RAW-Lucia™ ISG cells can be used to study the role of MAVS by monitoring of IRF-induced Lucia luciferase activity. They express the gene for secreted Lucia luciferase under the control of an IFN-inducible IFN-stimulated g
RAW-Lucia™ ISG cells signaling RAW-Lucia™ ISG cells were generated from the murine RAW 264.7 macrophage cell line by stable integration of an interferon regulatory factor (IRF)-inducible Lucia luciferase reporter construct. RAW 264.7 have been reported to express many pattern recognition receptors...
RAW-Lucia™ ISG-KO-cGAS Cells RAW-Lucia™ ISG-KO-IFI16 Cells RAW-Lucia™ ISG-KO-IRF1 Cells RAW-Lucia™ ISG-KO-IRF3 Cells RAW-Lucia™ ISG-KO-IRF5 Cells RAW-Lucia™ ISG-KO-IRF7 Cells RAW-Lucia™ ISG-KO-MAVS Cells RAW-Lucia™ ISG-KO-MDA5 Cells RAW-Lucia™ ISG-KO...
RAW-Lucia ISG-KO-IRF3 cells respond to murine type I IFNs but do not respond to cytosolic nucleic acids, such as poly(dA:dT)/LyoVec ,VACV70/LyoVec, poly(I:C)/LyoVec and 2'3'-cGAMP. RAW-Lucia™ ISG-KO-IRF3 cells are resistant toZeocin®. ...
RAW-Lucia™ ISG-KO-IFI16 cells can be used to study the importance of IFI16 in the induction of type I IFNs in response to nucleic acids. They allow the monitoring of IRF activation by determining the activity of Lucia luciferase. The levels of IRF-ind