Here's the deal: I'm 27 years old, which means I have been alive on this planet for10,000 days. During that time, I used alcohol on about1,500 days. Additionally, I used caffeine (from tea) about 1,500 times. Also during that time, I used ‘magic’ mushrooms 7 times, cannabis...
Naked mole rats live exponentially longer than other rodents. It is not unheard of for a mole rat to live 30 years or more, while the lifespan of amouseis about three years. Moreover, they do not seem to age. No one can really say why, though their DNA is able to repair itself o...
It was sometimes handy to plug in another mouse with a long cable on a rack mounted PC where there wasn’t enough realestate to use the mouse in the 19” rack keyboard drawer. This was before some bright spark invented the trackpad, and the upside down mouse aka a trackball. Now if ...
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After three rinses with TBST, tissue sections were incubated for 45 min at room temperature with AlexaFluor® 568-conjugated goat anti-mouse IgG (1:500 dilution, as above for primary antibody). Slides were rinsed with TBS, counterstained by applying DAPI (working concentration, 1 µg/...
Linagliptin, a Dipeptidyl Peptidase-4 Inhibitor, Mitigates Cognitive Deficits and Pathology in the 3xTg-AD Mouse Model of Alzheimer’s Disease Article 03 October 2016 Introduction DM has become the world’s fifth leading cause of death, and the International Diabetes Mellitus Federation estimated tha...
Finally, the larger size of the rat also allows for clinically relevant imaging (e.g. ultrasonography), with greater ease than in the mouse models. In conclusion, it was possible to establish a new model of HA for hemophilia A using the F8−/− rat model. The bleeding phenotype of ...
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(GSH) and cell viability in human keratinocyte HaCaT [6], spermatocyte cell line (GC2-spd) and Sertoli cell line (TM-4) of the mouse was reported [7], also increased lactate dehydrogenase (LDH) and downregulation of stress-related genes found on exposure to zinc oxide nanoparticles (ZNP)...
Secondary antibodies: Alexa Fluor 488 donkey anti-mouse IgG (1:200; Thermo Fisher Scientific Cat# R37114, RRID: AB_2556542) and Alexa Fluor 555 donkey anti-rabbit IgG (1:200; Thermo Fisher Scientific Cat# A-31572, RRID: AB_162543). The sections were counterstained with DAPI and examined...