Similar to Goodman’s approach, I submitted Freedom of Information requests to the NIH on the 11 responding institutions covered by state public records rules, asking for the “average daily inventory” data in the 11 institutions’ Assurance of Animal Welfare documents on file with the NIH OLAW....
Compared to mice, genetic manipulation in rats has been less advanced due to shortages of tools.22,23However, rats are more resemblance to human in physiology and behaviors than mice. Their larger body size makes it easier for surgical manipulations and for collecting blood/CSF samples.23More im...
The eyes of the mouse and rat differ mainly in size, by a linear scale factor of 1.9–2.0, and only slightly in refractive index. Thus refraction, chromatic aberration, and retinal illumination are easily compared in the two species. An analysis of the contribution of each optical surface to...
Again, Mas1 did not link to either locus. The lack of linkage between Mus Chr 17 and Mus Chr 7 homology segments in the deer mouse genome constituted the first example of a common breakpoint between the deer mouse and Mus genomes when compared to Rattus. Although uninformative for our ...
*P < 0.05, **P < 0.01, compared with respective control groups. SM: simulated microgravity. TS: tail-suspension. DownLoad: Full-Size Img PowerPoint DISCUSSION According to the duration of missions, astronauts may undergo short or long-term microgravity. Short-term microgravtiy usually induces...
DownLoad: Full-Size Img PowerPoint SiO2 Exposure Increases the Number of Fibrocytes in Blood or Lung Tissue As shown in Figure 6A and 6B, compared with the control group, the number of fibrocytes in blood was significantly increased at week 9. Furthermore, the number of fibrocytes in monodi...
Then, mouse laminin from Englebreth-Holm-Swarm tumor (Sigma L-2020 or Gibco catalog no. 23017-015; in 20 mmol/L Tris-HCl, 150 mmol/L NaCl, pH 7.2) was added to the fibril suspensions at a final laminin concentration as indicated in the legend of Figure 6. Th-T measurements were ...
Similar to other studies we observed less SR-BI in intact cycling female rats compared with male rats (8). However, we report for the first time that intact cycling female rats contain considerably more SR-BII than male rats. Ovariectomized female rats contained as much SR-BI as male rats ...
We reasoned that since the animals were free to interact with their cagemates in their home cage until 15 min prior to the exposure to stimuli, any significant induction of c-Fos expression in the brain following the social encounter, as compared to control animals, ought to be elicited ...
Peripheral insulin resistance and hyperandrogenism are the primary features of polycystic ovary syndrome (PCOS). However, how insulin resistance and hyperandrogenism affect uterine function and contribute to the pathogenesis of PCOS are open questions. W