Kinship behavior in the rat was first demonstrated by Hepper, who showed that from birth, pups recognize and respond preferentially to genetic relatives7,8. Similar to Hepper, we built a two-chamber apparatus connected by a center T-tube where air was blown through each box to the center of...
The animals were behaviorally tested for exposure effects from PND 37 to 64 using an operant procedure. Results: Exposure to PCB 153 was associated with pronounced and long-lasting behavioral changes in SHR/NCrl. Exposure effects in the SHR/NCrl depended on dose, where 1 mg/kg tended to ...
86 During each inter-trial interval, animals were removed from the arena and transferred back to the homecage, and the arena was cleaned to remove uncontrolled intra-maze non-visual cues. In some sessions, cells from four of the six implanted rats were additionally recorded in the same square...
Brito GNO, Brito LSO (1990): Septohippocampal system and the prelimbic sector of frontal cortex: A neuropsychological battery analysis in the rat. Behav Brain Res 36:127–146 Article Google Scholar Brito GNO, Thomas GJ (1981): T-maze alternation, response patterning, and septohippocampal circui...
Using a variety of delivery methods, including direct protein, stem cell and viral, GDNF has been shown to protect dopamine and motor neurons in a number of animal models.23–26 GDNF delivered into the spinal cord protected spinal motor neurons in ALS rats; however, it did not preserve ...
Under a Creative Commons license Open accessAbstract Using a novel rat model of Down syndrome (DS), the functional role of the cystathionine-β-synthase (CBS)/hydrogen sulfide (H2S) pathway was investigated on the pathogenesis of brain wave pattern alterations and neurobehavioral dysfunction. Increase...
Studies of the distribution of fluorescent-labeled Aβ1-42 in the brain showed that soluble Aβ-species diffused into all parts of the rat brain. After seven days, the Aβ-treated animals showed a significant decrease of spatial memory in Morris water maze test and impairment of synaptic ...