(residues 235‑488) chains linked by a disulfide bond. The light chain contains a Gla and two EGF‑like domains and the heavy chain corresponds to the serine protease domain. The full-length human Factor X was expressed and the pro enzyme was purified and activated. The active protease ...
Rat Heparin-Binding Epidermal Growth Factor Like-Growth Factor (HB-EGF) ELISA Kit Cat.No: MBS0117255) Do not remove microtiter plate from the storage bag until needed. Unused strips should be stored at 2-8掳C in their pouch with the desiccant provided.6) Use fresh disposable pipette tips ...
This EGF-like molecule induces cell differentiation and proliferation and contributes to wound healing and tissue repair following infection or injury29. In brain, AREG remarkably increases in response to ischemic conditions in cortical, striatal and hippocampal neurons, and attenuates neuronal damage by...
Storage of components varies. See protocol for specific instructions. Background: Betacellulin/BTC Betacellulin (BTC) is a member of the EGF (epidermal growth factor) family. The transmembrane BTC precursor undergoes proteolytic cleavage, releasing the BTC ligand. It binds to both EGFR/ErbB-1 an...
(EGF)-like domain, two to nine short consensus repeat (SCR) units, a transmembrane domain, and a cytoplasmic tail. L-Selectin expression is limited to hematopoietic cells, with most leukocytes expressing L-Selectin at some stage of differentiation. The majority of myeloid cells, B cells, and ...
Results indicated the levels of IL-6, Nuclear factor-κ B p65 (NF-κ B p65), signal transducers and activators of transcription 3 (STAT3), TNF-α , EGF, HGF, ERK-1/2 and YAP were significantly increased in the ALPPS group compared with the other groups, suggesting that these ...
(aa 21-1725) plus a 159 aa cytoplasmic region (aa 1747-1905). In the ECD, there are eight LDLR class A repeats (aa 26-350), two EGF-like repeats (aa 354-434) and 20 LDLR class B repeats that contain an intervening EGF-like domain (aa 480-1610). Over aa 18-344, human LRP...
MILLIPLEX® Rat Kidney Toxicity Magnetic Bead Panel 2 - Toxicity Multiplex Assay The analytes available for this multiplex kit are: Albumin, AGP, ß2M, Cystatin C, EGF, Lipocalin-2/NGAL. at Sigma-Aldrich
an amino-terminal domain, eight EGF-like repeats and 27 Cub domains. Co-expression with amnionless is required for the membrane anchoring, ER export and internalizing action of Cubilin. Within the region used as the immunogen, human, mouse and rat Cubilin share approximately 76% amino acid sequ...
Mature rat DLL1 consists of a 520 amino acid (aa) extracellular domain (ECD) with one DSL domain and eight EGF-like repeats, a 23 aa transmembrane segment, and a 154 aa cytoplasmic domain (1). Within the ECD, rat DLL1 shares 90% and 95% aa sequence identity with human and mouse ...