(2015) The RAS-RAL axis in cancer: evidence for mutation-specific selectivity in non-small cell lung cancer. Acta Pharmacol. Sin. 36, 291-297Guin, S. & Theodorescu, D. The RAS-RAL axis in cancer: evidence for mutation-specific selectivity in non-small cell lung cancer. Acta Pharmacol....
RAS是三区，RAM和RAL都是二区。这三者都很不错，在机器人领域都是拿得出手的文章，但RAM审稿比较久...
RAL认可度最高，现在是二区top，审稿三个月左右。RAS就别投了，太慢了，三区。RAS、RAM和RA-L都是...
Ras相关蛋白Ral-A(RALA)抗体 英文名称: Ras-Related Protein Ral-A (RALA) Antibody 品牌: Abbexa 货号: abx000750 规格: 20 µl 价格: $174 产品说明书下载: 产品预定 >> 产品预定,提交订单信息之后,我们会第一时间与您取得联系 一抗一抗 货号 产品名称 规格 价格 指令 abx000001 组蛋白H3K27AC抗体...
Tumors generated in this animal model will be analyzed to determine the extent of R-Ras and Ral-A activity in vivo. This study demonstrates the importance of the RASA1/R-Ras/Ral-A signaling pathway in BRAF mutant melanoma and supports the possible combinatorial treatment strategy targeting both...
Furthermore, the modified form of Ral bound to Ral-binding protein 1 (RalBP1), a putative effector protein of Ral, more effectively than the unmodified form. Taken together with the observations that Ras and Ral are localized to the membranes, these results suggest that the post-translational ...
Cytoskeleton provides RhoA, Rac1, Cdc42, small g-proteins, gtpase, pulldown, cell motility, cell shape, glisa, lamellipodia, filopodia, microspikes, focal adhesions, Ras p21, H-Ras, K-Ras, Arf1, Arf6, cytoskeleton, protein, RhoA gtpase, Rac gtpase, Ras g
However, these efforts are complicated by the fact that Ras can utilize at least 9 additional functionally distinct effectors, with at least 3 additional effectors with validated roles in Ras-mediated oncogenesis. Of these, the guanine nucleotide exchange factors of the Ras-like (Ral) small GT...
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Molecularly, upregulation of Ral GTPase activity and Sox9 expression underlies the observed phenotypes, identifying a previously unrecognized function of Ral signalling in ADM. Our results provide evidence for a tumour suppressive role of κB-Ras proteins and highlight low κB-Ras levels and consequent...