2024年8月30日,在欧洲心脏病学会年会(ESC 2024)HOT LINE 1专场上,来自美国加州大学旧金山分校的Matthieu Legrand教授将公布随机对照试验STOP-or-NOT研究结果。POCKETIN基于该研究已发表的研究设计文章,特整理概述,以供速览。 研究背景 高...
RAS blockade with angiotensin (Ang) 1-converting enzyme inhibitors (ACEIs) or Ang II type 1 receptor blockers (ARBs) is beneficial in such conditions. However, aldosterone secretion can persist despite these treatments. Hence, mechanisms besides Ang II acquire the role of aldosterone secretagogue....
Ki-ras activation by point mutation is known to be involved in the early, adenoma phase of evolution of colorectal tumorigenesis, but these results show that differential expression of the mutant allele is common in carcinomas and may be associated with persisting growth advantage. 展开 ...